LINC01122

Summary

LINC01122 (long intergenic non-protein coding RNA 1122, HGNC:49267) is a long non-coding RNA gene on chromosome 2p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49267
Approved symbol	LINC01122
Name	long intergenic non-protein coding RNA 1122
Location	2p16.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.54, uc.53, uc.52, FLJ30838, AC007092.1
Ensembl gene	ENSG00000233723
Ensembl biotype	lncRNA
Entrez	400955
RNAcentral	URS000075E2F0 — lncRNA, 4313 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 68 — 68 lncRNA

ENST00000409590, ENST00000422723, ENST00000422793, ENST00000427421, ENST00000429095, ENST00000429664, ENST00000449448, ENST00000452840, ENST00000455219, ENST00000650010, ENST00000650056, ENST00000655072, ENST00000656135, ENST00000656193, ENST00000656381, ENST00000657130, ENST00000657378, ENST00000662396, ENST00000663407, ENST00000664741, ENST00000665429, ENST00000665478, ENST00000665525, ENST00000668410, ENST00000669630, ENST00000671194, ENST00000684946, ENST00000687108, ENST00000701416, ENST00000702114, ENST00000715766, ENST00000821268, ENST00000821269, ENST00000821270, ENST00000821271, ENST00000821272, ENST00000821273, ENST00000821274, ENST00000821275, ENST00000821276, ENST00000821277, ENST00000821278, ENST00000821279, ENST00000821280, ENST00000821281, ENST00000821282, ENST00000821283, ENST00000821284, ENST00000821285, ENST00000821286, ENST00000821287, ENST00000821288, ENST00000821289, ENST00000821290, ENST00000821291, ENST00000821292, ENST00000821293, ENST00000821294, ENST00000821295, ENST00000821296, ENST00000821297, ENST00000821298, ENST00000821299, ENST00000821300, ENST00000821301, ENST00000821302, ENST00000821303, ENST00000821304

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000409590 — 3 exons

Exon	Start	End
ENSE00001582873	59277532	59279400
ENSE00001583798	59217708	59217774
ENSE00001587112	59255163	59255262

Expression profiles

Bgee: expression breadth ubiquitous, 142 present calls, max score 88.83.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9432 / max 91.2179, expressed in 270 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
20418	0.4795	146
20420	0.2706	114
20419	0.1269	43
20422	0.0454	15
20417	0.0208	5

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	88.83	gold quality
ganglionic eminence	UBERON:0004023	84.54	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.35	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.91	gold quality
bone marrow cell	CL:0002092	73.67	silver quality
prefrontal cortex	UBERON:0000451	73.24	gold quality
ventricular zone	UBERON:0003053	72.17	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.87	gold quality
right frontal lobe	UBERON:0002810	70.83	gold quality
nucleus accumbens	UBERON:0001882	69.53	gold quality
anterior cingulate cortex	UBERON:0009835	69.18	gold quality
putamen	UBERON:0001874	68.33	gold quality
neocortex	UBERON:0001950	67.27	gold quality
frontal cortex	UBERON:0001870	66.77	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.70	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.63	gold quality
caudate nucleus	UBERON:0001873	66.51	gold quality
hypothalamus	UBERON:0001898	65.91	gold quality
sural nerve	UBERON:0015488	65.18	gold quality
spinal cord	UBERON:0002240	64.24	gold quality
amygdala	UBERON:0001876	63.79	gold quality
cerebral cortex	UBERON:0000956	63.56	gold quality
forebrain	UBERON:0001890	62.94	gold quality
corpus callosum	UBERON:0002336	61.83	gold quality
brain	UBERON:0000955	61.24	gold quality
substantia nigra	UBERON:0002038	60.66	gold quality
buccal mucosa cell	CL:0002336	60.57	silver quality
adrenal tissue	UBERON:0018303	60.11	gold quality
midbrain	UBERON:0001891	58.19	gold quality
Ammon’s horn	UBERON:0001954	58.10	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-HCAD-35	yes	91.89
E-ANND-3	no	4.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.