LINC01127

Summary

LINC01127 (long intergenic non-protein coding RNA 1127, HGNC:49292) is a long non-coding RNA gene on chromosome 2q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49292
Approved symbol	LINC01127
Name	long intergenic non-protein coding RNA 1127
Location	2q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000281162
Ensembl biotype	lncRNA
Entrez	100506328
RNAcentral	URS000075DF7A — lncRNA, 996 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000625702, ENST00000627215, ENST00000627273, ENST00000627337, ENST00000628502, ENST00000692650, ENST00000702456, ENST00000702641, ENST00000702898, ENST00000723061, ENST00000723062, ENST00000723063, ENST00000723064, ENST00000723065, ENST00000723066, ENST00000723067, ENST00000723068, ENST00000723069, ENST00000723070, ENST00000723071, ENST00000723072, ENST00000723073, ENST00000723074, ENST00000723075, ENST00000723076, ENST00000723077, ENST00000723078

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000625702 — 3 exons

Exon	Start	End
ENSE00003760607	101983465	101983578
ENSE00003769277	101984584	101985105
ENSE00003769474	101983692	101983821

Expression profiles

Bgee: expression breadth ubiquitous, 141 present calls, max score 82.53.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5048 / max 103.0001, expressed in 143 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
21647	0.2168	88
21646	0.1399	50
21649	0.0988	19
202324	0.0292	12
21648	0.0201	9

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	82.53	gold quality
blood	UBERON:0000178	80.82	gold quality
right lobe of liver	UBERON:0001114	78.38	gold quality
tonsil	UBERON:0002372	77.36	gold quality
liver	UBERON:0002107	75.11	gold quality
epithelium of nasopharynx	UBERON:0001951	73.97	silver quality
leukocyte	CL:0000738	73.00	gold quality
monocyte	CL:0000576	72.82	gold quality
granulocyte	CL:0000094	72.01	gold quality
right lung	UBERON:0002167	69.99	gold quality
spleen	UBERON:0002106	67.67	gold quality
bone marrow cell	CL:0002092	67.38	silver quality
vermiform appendix	UBERON:0001154	67.13	gold quality
cortical plate	UBERON:0005343	66.70	gold quality
endocervix	UBERON:0000458	63.30	gold quality
caecum	UBERON:0001153	61.30	gold quality
right lobe of thyroid gland	UBERON:0001119	60.73	gold quality
left lobe of thyroid gland	UBERON:0001120	60.45	gold quality
stromal cell of endometrium	CL:0002255	59.18	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.94	gold quality
thyroid gland	UBERON:0002046	58.77	gold quality
esophagus mucosa	UBERON:0002469	58.18	gold quality
metanephros cortex	UBERON:0010533	57.67	gold quality
upper lobe of left lung	UBERON:0008952	57.13	gold quality
left uterine tube	UBERON:0001303	57.05	gold quality
upper lobe of lung	UBERON:0008948	56.26	gold quality
smooth muscle tissue	UBERON:0001135	56.06	gold quality
lower esophagus mucosa	UBERON:0035834	55.99	gold quality
cortex of kidney	UBERON:0001225	55.00	gold quality
esophagus	UBERON:0001043	53.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.05

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.