LINC01132

Summary

LINC01132 (long intergenic non-protein coding RNA 1132, HGNC:49444) is a long non-coding RNA gene on chromosome 1q42.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49444
Approved symbol	LINC01132
Name	long intergenic non-protein coding RNA 1132
Location	1q42.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227630
Ensembl biotype	lncRNA
Entrez	100506810
RNAcentral	URS0000127952 — lncRNA, 3793 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000437601, ENST00000641214, ENST00000642107, ENST00000662158, ENST00000762106, ENST00000762107, ENST00000762108, ENST00000762109, ENST00000762110

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437601 — 3 exons

Exon	Start	End
ENSE00001641862	234728348	234731643
ENSE00001799592	234725223	234725678
ENSE00003698941	234724042	234724082

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 68.56.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5366 / max 47.1520, expressed in 163 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
9147	0.3499	76
9148	0.1139	65
9146	0.0728	28

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	68.56	silver quality
sural nerve	UBERON:0015488	62.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.60	gold quality
cortical plate	UBERON:0005343	60.32	silver quality
hindlimb stylopod muscle	UBERON:0004252	60.16	silver quality
ventricular zone	UBERON:0003053	59.51	gold quality
bone marrow	UBERON:0002371	59.24	gold quality
islet of Langerhans	UBERON:0000006	57.79	gold quality
right uterine tube	UBERON:0001302	57.79	gold quality
skeletal muscle tissue	UBERON:0001134	57.06	gold quality
fallopian tube	UBERON:0003889	56.91	gold quality
prefrontal cortex	UBERON:0000451	55.16	gold quality
leukocyte	CL:0000738	53.33	silver quality
pancreas	UBERON:0001264	53.25	gold quality
monocyte	CL:0000576	52.74	silver quality
nucleus accumbens	UBERON:0001882	52.58	gold quality
saliva-secreting gland	UBERON:0001044	52.48	gold quality
minor salivary gland	UBERON:0001830	52.08	gold quality
granulocyte	CL:0000094	51.82	gold quality
adult mammalian kidney	UBERON:0000082	51.16	gold quality
myometrium	UBERON:0001296	51.11	gold quality
pituitary gland	UBERON:0000007	50.94	gold quality
kidney	UBERON:0002113	50.76	gold quality
frontal cortex	UBERON:0001870	50.75	gold quality
duodenum	UBERON:0002114	50.62	gold quality
liver	UBERON:0002107	50.42	gold quality
lymph node	UBERON:0000029	50.38	gold quality
smooth muscle tissue	UBERON:0001135	50.37	gold quality
muscle of leg	UBERON:0001383	50.33	gold quality
right lobe of liver	UBERON:0001114	50.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.20

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Silencing of the long noncoding RNA LINC01132 alleviates the oncogenicity of epithelial ovarian cancer by regulating the microRNA4315p/SOX9 axis. (PMID:34132375)
• Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma. (PMID:36071454)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.