LINC01134

Summary

LINC01134 (long intergenic non-protein coding RNA 1134, HGNC:49449) is a long non-coding RNA gene on chromosome 1p36.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49449
Approved symbol	LINC01134
Name	long intergenic non-protein coding RNA 1134
Location	1p36.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	TLNC1
Ensembl gene	ENSG00000236423
Ensembl biotype	lncRNA
Entrez	100133612
RNAcentral	URS0000759EB6 — lncRNA, 1965 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000413332, ENST00000439488, ENST00000442673, ENST00000667408, ENST00000686089, ENST00000693306, ENST00000757265, ENST00000757266, ENST00000757267, ENST00000757268, ENST00000757269, ENST00000757270, ENST00000757271, ENST00000757272, ENST00000757273, ENST00000757274, ENST00000757275, ENST00000757276, ENST00000757277, ENST00000757278, ENST00000757279, ENST00000757280, ENST00000757281, ENST00000757282

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413332 — 3 exons

Exon	Start	End
ENSE00001678312	3903965	3904036
ENSE00003981733	3900347	3900631
ENSE00004108214	3905231	3906110

Expression profiles

Bgee: expression breadth ubiquitous, 164 present calls, max score 75.68.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6784 / max 23.7365, expressed in 365 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
330	0.6784	365

Top tissues by expression

220 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	75.68	gold quality
right testis	UBERON:0004534	72.62	gold quality
tendon	UBERON:0000043	71.50	gold quality
left testis	UBERON:0004533	71.48	gold quality
tendon of biceps brachii	UBERON:0008188	70.69	gold quality
testis	UBERON:0000473	69.64	gold quality
apex of heart	UBERON:0002098	67.75	gold quality
mucosa of transverse colon	UBERON:0004991	67.59	gold quality
ganglionic eminence	UBERON:0004023	66.91	gold quality
myocardium	UBERON:0002349	66.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.68	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.46	gold quality
biceps brachii	UBERON:0001507	63.94	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	63.94	gold quality
amniotic fluid	UBERON:0000173	63.87	gold quality
secondary oocyte	CL:0000655	63.76	gold quality
lower lobe of lung	UBERON:0008949	63.61	silver quality
oral cavity	UBERON:0000167	62.95	gold quality
oocyte	CL:0000023	62.71	gold quality
gingival epithelium	UBERON:0001949	62.66	gold quality
skeletal muscle tissue	UBERON:0001134	62.27	gold quality
muscle of leg	UBERON:0001383	62.23	gold quality
mammary duct	UBERON:0001765	62.22	gold quality
gingiva	UBERON:0001828	62.14	gold quality
gastrocnemius	UBERON:0001388	62.11	gold quality
jejunum	UBERON:0002115	61.76	gold quality
lower esophagus mucosa	UBERON:0035834	61.13	gold quality
monocyte	CL:0000576	61.00	gold quality
substantia nigra pars compacta	UBERON:0001965	60.95	silver quality
parotid gland	UBERON:0001831	60.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.09

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LSD1-Demethylated LINC01134 Confers Oxaliplatin Resistance Through SP1-Induced p62 Transcription in HCC. (PMID:34322883)
• FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC. (PMID:37914721)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.