LINC01141

Summary

LINC01141 (long intergenic non-protein coding RNA 1141, HGNC:49455) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49455
Approved symbol	LINC01141
Name	long intergenic non-protein coding RNA 1141
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236963
Ensembl biotype	lncRNA
Entrez	339505
RNAcentral	URS000075A082 — lncRNA, 3799 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 75 — 75 lncRNA

ENST00000418743, ENST00000423486, ENST00000426428, ENST00000635564, ENST00000635577, ENST00000652870, ENST00000660748, ENST00000661413, ENST00000662632, ENST00000666314, ENST00000670217, ENST00000686000, ENST00000686048, ENST00000690112, ENST00000690859, ENST00000691289, ENST00000691512, ENST00000691881, ENST00000693117, ENST00000693701, ENST00000702538, ENST00000702704, ENST00000816624, ENST00000816625, ENST00000816626, ENST00000816627, ENST00000816628, ENST00000816629, ENST00000816630, ENST00000816631, ENST00000816632, ENST00000816633, ENST00000816634, ENST00000816635, ENST00000816636, ENST00000816637, ENST00000816638, ENST00000816639, ENST00000816640, ENST00000816641, ENST00000816642, ENST00000816643, ENST00000816644, ENST00000816645, ENST00000816646, ENST00000816647, ENST00000816648, ENST00000816649, ENST00000816650, ENST00000816651, ENST00000816652, ENST00000816653, ENST00000816654, ENST00000816655, ENST00000816656, ENST00000816657, ENST00000816658, ENST00000816659, ENST00000816660, ENST00000816661, ENST00000816662, ENST00000816663, ENST00000816664, ENST00000816665, ENST00000816666, ENST00000816667, ENST00000816668, ENST00000816669, ENST00000816670, ENST00000816671, ENST00000816672, ENST00000816673, ENST00000816674, ENST00000816675, ENST00000816676

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418743 — 5 exons

Exon	Start	End
ENSE00001686897	20398483	20398787
ENSE00001714967	20405575	20405694
ENSE00001800935	20406187	20406269
ENSE00003984438	20398085	20398225
ENSE00003984439	20428584	20429202

Expression profiles

Bgee: expression breadth ubiquitous, 137 present calls, max score 82.21.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1146 / max 12.3229, expressed in 60 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10723	0.0593	40
10724	0.0357	29
10725	0.0196	11

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.21	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	78.27	gold quality
spinal cord	UBERON:0002240	74.88	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.14	gold quality
anterior cingulate cortex	UBERON:0009835	73.02	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.32	gold quality
left testis	UBERON:0004533	71.88	gold quality
right frontal lobe	UBERON:0002810	71.50	gold quality
right testis	UBERON:0004534	70.67	gold quality
ventricular zone	UBERON:0003053	70.01	gold quality
amygdala	UBERON:0001876	69.89	gold quality
testis	UBERON:0000473	69.00	gold quality
substantia nigra	UBERON:0002038	68.63	gold quality
hypothalamus	UBERON:0001898	68.43	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	67.54	gold quality
putamen	UBERON:0001874	66.74	gold quality
caudate nucleus	UBERON:0001873	66.20	gold quality
nucleus accumbens	UBERON:0001882	65.36	gold quality
ganglionic eminence	UBERON:0004023	65.26	gold quality
midbrain	UBERON:0001891	65.23	gold quality
prefrontal cortex	UBERON:0000451	64.76	gold quality
neocortex	UBERON:0001950	64.41	gold quality
cortical plate	UBERON:0005343	62.89	gold quality
frontal cortex	UBERON:0001870	62.73	gold quality
cerebral cortex	UBERON:0000956	62.42	gold quality
forebrain	UBERON:0001890	61.51	gold quality
brain	UBERON:0000955	60.43	gold quality
Ammon’s horn	UBERON:0001954	60.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.14	gold quality
cerebellar vermis	UBERON:0004720	58.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.