LINC01143

Summary

LINC01143 (long intergenic non-protein coding RNA 1143, HGNC:49458) is a long non-coding RNA gene on chromosome 2p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49458
Approved symbol	LINC01143
Name	long intergenic non-protein coding RNA 1143
Location	2p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237751
Ensembl biotype	lncRNA
Entrez	104355141
RNAcentral	URS00007E39FB — lncRNA, 654 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000449073, ENST00000741192, ENST00000741193, ENST00000741194

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449073 — 4 exons

Exon	Start	End
ENSE00001753878	70888286	70888348
ENSE00002445702	70889476	70889588
ENSE00004078118	70889821	70889983
ENSE00004078120	70887871	70888180

Expression profiles

Bgee: expression breadth broad, 82 present calls, max score 89.25.

Top tissues by expression

82 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.25	gold quality
cortex of kidney	UBERON:0001225	65.94	gold quality
colonic epithelium	UBERON:0000397	65.50	silver quality
skeletal muscle tissue	UBERON:0001134	63.09	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.01	gold quality
body of pancreas	UBERON:0001150	57.38	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.78	gold quality
pancreas	UBERON:0001264	56.42	gold quality
urinary bladder	UBERON:0001255	54.30	gold quality
islet of Langerhans	UBERON:0000006	51.57	gold quality
myometrium	UBERON:0001296	50.56	gold quality
blood	UBERON:0000178	49.84	silver quality
monocyte	CL:0000576	49.55	silver quality
muscle of leg	UBERON:0001383	49.40	gold quality
smooth muscle tissue	UBERON:0001135	49.05	gold quality
cerebellar cortex	UBERON:0002129	49.01	gold quality
cerebellar hemisphere	UBERON:0002245	48.98	gold quality
placenta	UBERON:0001987	48.69	gold quality
right hemisphere of cerebellum	UBERON:0014890	48.16	gold quality
omental fat pad	UBERON:0010414	47.46	gold quality
gastrocnemius	UBERON:0001388	47.44	silver quality
endocervix	UBERON:0000458	47.37	gold quality
spleen	UBERON:0002106	46.86	gold quality
endometrium	UBERON:0001295	46.85	gold quality
adipose tissue	UBERON:0001013	46.81	gold quality
Ammon’s horn	UBERON:0001954	46.26	gold quality
thoracic mammary gland	UBERON:0005200	46.24	gold quality
body of uterus	UBERON:0009853	46.22	gold quality
left coronary artery	UBERON:0001626	45.76	gold quality
skin of abdomen	UBERON:0001416	45.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.