LINC01149

Summary

LINC01149 (long intergenic non-protein coding RNA 1149, HGNC:39757) is a long non-coding RNA gene on chromosome 6p21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39757
Approved symbol	LINC01149
Name	long intergenic non-protein coding RNA 1149
Location	6p21.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	XXbac-BPG181B23.4
Ensembl gene	ENSG00000230174
Ensembl biotype	lncRNA
Entrez	101929111
RNAcentral	URS0000A76761 — lncRNA, 2156 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000430364, ENST00000812003

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430364 — 2 exons

Exon	Start	End
ENSE00001665233	31445478	31446973
ENSE00001689076	31441667	31442311

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 85.33.

Top tissues by expression

34 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.33	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.90	silver quality
ventricular zone	UBERON:0003053	57.57	silver quality
pancreas	UBERON:0001264	55.48	silver quality
ganglionic eminence	UBERON:0004023	54.47	silver quality
body of stomach	UBERON:0001161	50.93	gold quality
right testis	UBERON:0004534	50.03	gold quality
testis	UBERON:0000473	48.19	gold quality
blood	UBERON:0000178	48.02	silver quality
left testis	UBERON:0004533	48.02	gold quality
right adrenal gland cortex	UBERON:0035827	46.17	gold quality
left coronary artery	UBERON:0001626	44.76	gold quality
tibial nerve	UBERON:0001323	44.24	silver quality
gastrocnemius	UBERON:0001388	43.30	silver quality
tibial artery	UBERON:0007610	42.33	silver quality
ovary	UBERON:0000992	41.38	silver quality
right atrium auricular region	UBERON:0006631	41.35	silver quality
right hemisphere of cerebellum	UBERON:0014890	41.23	silver quality
ascending aorta	UBERON:0001496	40.92	silver quality
muscle layer of sigmoid colon	UBERON:0035805	40.86	silver quality
amygdala	UBERON:0001876	40.83	silver quality
myometrium	UBERON:0001296	40.68	silver quality
caudate nucleus	UBERON:0001873	39.29	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	39.19	silver quality
lower esophagus muscularis layer	UBERON:0035833	38.99	silver quality
transverse colon	UBERON:0001157	38.93	silver quality
omental fat pad	UBERON:0010414	38.84	silver quality
left ovary	UBERON:0002119	38.10	silver quality
subcutaneous adipose tissue	UBERON:0002190	37.96	silver quality
skin of leg	UBERON:0001511	37.83	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01149 variant modulates MICA expression that facilitates hepatitis B virus spontaneous recovery but increases hepatocellular carcinoma risk. (PMID:31754211)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.