LINC01173

Summary

LINC01173 (long intergenic non-protein coding RNA 1173, HGNC:49545) is a long non-coding RNA gene on chromosome 2q37.1-q37.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49545
Approved symbol	LINC01173
Name	long intergenic non-protein coding RNA 1173
Location	2q37.1-q37.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00004057
Ensembl gene	ENSG00000280744
Ensembl biotype	lncRNA
Entrez	106144537
RNAcentral	URS0000811C76 — lncRNA, 331 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000629370, ENST00000768858, ENST00000768859, ENST00000768860, ENST00000768861

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000629370 — 4 exons

Exon	Start	End
ENSE00003764252	234717635	234717764
ENSE00003767364	234695649	234695748
ENSE00004129546	234682556	234682768
ENSE00004129549	234723133	234723480

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 86.28.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2311 / max 37.8551, expressed in 100 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
26164	0.1020	50
26163	0.0692	23
26162	0.0600	18

Top tissues by expression

41 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.28	gold quality
muscle of leg	UBERON:0001383	73.09	gold quality
gastrocnemius	UBERON:0001388	61.97	gold quality
placenta	UBERON:0001987	61.33	gold quality
liver	UBERON:0002107	59.97	gold quality
tibial artery	UBERON:0007610	59.52	gold quality
islet of Langerhans	UBERON:0000006	58.83	gold quality
stomach	UBERON:0000945	57.74	gold quality
monocyte	CL:0000576	54.13	gold quality
upper lobe of left lung	UBERON:0008952	52.93	gold quality
tibial nerve	UBERON:0001323	51.47	gold quality
myometrium	UBERON:0001296	51.46	gold quality
lower esophagus muscularis layer	UBERON:0035833	51.00	gold quality
right lobe of liver	UBERON:0001114	50.64	gold quality
adrenal tissue	UBERON:0018303	49.69	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	49.27	gold quality
substantia nigra	UBERON:0002038	48.13	gold quality
subcutaneous adipose tissue	UBERON:0002190	47.70	gold quality
multicellular organism	UBERON:0000468	47.60	gold quality
Ammon’s horn	UBERON:0001954	46.49	gold quality
omental fat pad	UBERON:0010414	46.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	45.88	gold quality
spleen	UBERON:0002106	45.52	gold quality
esophagus mucosa	UBERON:0002469	45.17	gold quality
hypothalamus	UBERON:0001898	45.07	gold quality
pituitary gland	UBERON:0000007	44.68	gold quality
zone of skin	UBERON:0000014	44.61	gold quality
adenohypophysis	UBERON:0002196	44.50	gold quality
skin of abdomen	UBERON:0001416	43.38	gold quality
nucleus accumbens	UBERON:0001882	43.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.