LINC01187

Summary

LINC01187 (long intergenic non-protein coding RNA 1187, HGNC:49575) is a long non-coding RNA gene on chromosome 5q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49575
Approved symbol	LINC01187
Name	long intergenic non-protein coding RNA 1187
Location	5q35.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	KIDR
Ensembl gene	ENSG00000249601
Ensembl biotype	lncRNA
Entrez	100507267
RNAcentral	URS000075C826 — lncRNA, 1334 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000506431, ENST00000520275

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506431 — 4 exons

Exon	Start	End
ENSE00002020563	170191579	170192263
ENSE00002026031	170197752	170199141
ENSE00002043805	170193916	170194006
ENSE00002050516	170196484	170196631

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 90.85.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0205 / max 12.9164, expressed in 7 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
64754	0.0205	7

Top tissues by expression

193 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
metanephros cortex	UBERON:0010533	90.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	89.19	gold quality
cortex of kidney	UBERON:0001225	86.15	gold quality
adult mammalian kidney	UBERON:0000082	86.01	gold quality
kidney	UBERON:0002113	81.64	gold quality
kidney epithelium	UBERON:0004819	75.66	gold quality
metanephros	UBERON:0000081	73.86	gold quality
renal medulla	UBERON:0000362	70.13	gold quality
tibialis anterior	UBERON:0001385	67.17	silver quality
epithelial cell of pancreas	CL:0000083	64.54	gold quality
buccal mucosa cell	CL:0002336	63.68	gold quality
cerebellar vermis	UBERON:0004720	62.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.41	gold quality
pancreatic ductal cell	CL:0002079	60.73	silver quality
minor salivary gland	UBERON:0001830	59.72	gold quality
skin of hip	UBERON:0001554	58.94	gold quality
ileal mucosa	UBERON:0000331	57.17	silver quality
saliva-secreting gland	UBERON:0001044	56.96	gold quality
mouth mucosa	UBERON:0003729	56.89	gold quality
deltoid	UBERON:0001476	56.52	gold quality
muscle of leg	UBERON:0001383	54.68	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
tendon of biceps brachii	UBERON:0008188	54.28	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
granulocyte	CL:0000094	52.56	gold quality
monocyte	CL:0000576	52.34	silver quality
cartilage tissue	UBERON:0002418	51.75	gold quality
gastrocnemius	UBERON:0001388	51.08	silver quality
nasal cavity mucosa	UBERON:0001826	50.89	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 3.

Experiment	Marker?	Max mean expression
E-GEOD-131882	yes	1385.83
E-CURD-119	yes	47.27
E-ANND-3	yes	2.61

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Down-regulation of human long non-coding RNA LINC01187 is associated with nephropathies. (PMID:37056054)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.