LINC01194

Summary

LINC01194 (long intergenic non-protein coding RNA 1194, HGNC:37171) is a long non-coding RNA gene on chromosome 5p15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37171
Approved symbol	LINC01194
Name	long intergenic non-protein coding RNA 1194
Location	5p15.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	TAG
Ensembl gene	ENSG00000248131
Ensembl biotype	lncRNA
OMIM	617097
Entrez	404663
RNAcentral	URS0000759BD5 — lncRNA, 624 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000505196, ENST00000505877, ENST00000513051, ENST00000658959, ENST00000664069, ENST00000839367, ENST00000839368, ENST00000839369, ENST00000839370, ENST00000839371, ENST00000839372, ENST00000839373, ENST00000839374

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505196 — 4 exons

Exon	Start	End
ENSE00002023019	12574857	12575052
ENSE00002038284	12804204	12804363
ENSE00002067011	12595697	12595778
ENSE00002086619	12711198	12711299

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 85.32.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2388 / max 21.3455, expressed in 85 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55727	0.2388	85

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.32	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.49	gold quality
sural nerve	UBERON:0015488	72.47	silver quality
hindlimb stylopod muscle	UBERON:0004252	68.56	gold quality
placenta	UBERON:0001987	66.91	gold quality
duodenum	UBERON:0002114	64.09	gold quality
lower esophagus mucosa	UBERON:0035834	58.98	gold quality
calcaneal tendon	UBERON:0003701	58.70	gold quality
cortex of kidney	UBERON:0001225	58.26	gold quality
lymph node	UBERON:0000029	58.08	gold quality
granulocyte	CL:0000094	56.50	gold quality
monocyte	CL:0000576	55.83	gold quality
blood	UBERON:0000178	54.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.99	gold quality
fundus of stomach	UBERON:0001160	52.40	gold quality
liver	UBERON:0002107	52.03	gold quality
prefrontal cortex	UBERON:0000451	51.49	gold quality
vermiform appendix	UBERON:0001154	51.45	gold quality
muscle of leg	UBERON:0001383	51.12	gold quality
right lobe of liver	UBERON:0001114	50.09	gold quality
spleen	UBERON:0002106	50.07	gold quality
substantia nigra	UBERON:0002038	49.16	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	49.11	gold quality
gastrocnemius	UBERON:0001388	48.61	gold quality
heart left ventricle	UBERON:0002084	48.32	gold quality
prostate gland	UBERON:0002367	48.10	gold quality
esophagus mucosa	UBERON:0002469	47.89	gold quality
Ammon’s horn	UBERON:0001954	47.77	gold quality
smooth muscle tissue	UBERON:0001135	47.66	gold quality
myometrium	UBERON:0001296	47.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.11

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 4)

• Long noncoding RNA LINC01194 enhances the malignancy of laryngeal squamous cell carcinoma by sponging miR-655 to increase SOX18 expression. (PMID:32703403)
• PAX5-induced upregulation of LINC01194 exerts oncogenic properties by regulating GOLPH3 expression via miR-486-5p in prostate cancer. (PMID:33829439)
• LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer. (PMID:35750275)
• LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1. (PMID:38072399)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.