LINC01235

Summary

LINC01235 (long intergenic non-protein coding RNA 1235, HGNC:49769) is a long non-coding RNA gene on chromosome 9p23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49769
Approved symbol	LINC01235
Name	long intergenic non-protein coding RNA 1235
Location	9p23
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ41200
Ensembl gene	ENSG00000270547
Ensembl biotype	lncRNA
Entrez	401492
RNAcentral	URS000075C555 — lncRNA, 2330 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000604724, ENST00000605459, ENST00000655038, ENST00000661860, ENST00000663740, ENST00000668698, ENST00000840310, ENST00000840311, ENST00000840312, ENST00000840313, ENST00000840314, ENST00000840315, ENST00000840316, ENST00000840317, ENST00000840318

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000604724 — 4 exons

Exon	Start	End
ENSE00003537226	13416399	13416545
ENSE00003873755	13432901	13433025
ENSE00004263473	13431203	13431438
ENSE00004263475	13406323	13408433

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 71.37.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 1.5810 / max 614.3996, expressed in 114 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
99964	1.5452	114
99963	0.0359	13

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thoracic mammary gland	UBERON:0005200	71.37	gold quality
right lobe of thyroid gland	UBERON:0001119	69.75	gold quality
omental fat pad	UBERON:0010414	68.17	gold quality
minor salivary gland	UBERON:0001830	67.91	gold quality
saliva-secreting gland	UBERON:0001044	67.81	gold quality
lymph node	UBERON:0000029	66.50	gold quality
colonic epithelium	UBERON:0000397	65.23	silver quality
adipose tissue	UBERON:0001013	64.09	gold quality
thyroid gland	UBERON:0002046	64.02	gold quality
left lobe of thyroid gland	UBERON:0001120	63.87	gold quality
urinary bladder	UBERON:0001255	63.32	gold quality
ventricular zone	UBERON:0003053	62.42	gold quality
substantia nigra	UBERON:0002038	61.60	gold quality
subcutaneous adipose tissue	UBERON:0002190	60.82	gold quality
ganglionic eminence	UBERON:0004023	60.72	gold quality
calcaneal tendon	UBERON:0003701	60.28	gold quality
right atrium auricular region	UBERON:0006631	60.05	gold quality
tonsil	UBERON:0002372	59.79	gold quality
left coronary artery	UBERON:0001626	59.26	gold quality
gall bladder	UBERON:0002110	58.76	gold quality
body of stomach	UBERON:0001161	58.14	gold quality
stomach	UBERON:0000945	57.50	gold quality
skin of leg	UBERON:0001511	57.47	gold quality
zone of skin	UBERON:0000014	57.33	gold quality
skin of abdomen	UBERON:0001416	57.24	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.14	gold quality
hypothalamus	UBERON:0001898	57.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.94	gold quality
cortical plate	UBERON:0005343	56.86	gold quality
ascending aorta	UBERON:0001496	56.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.34

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LINC01235-TWIST2 feedback loop facilitates epithelial-mesenchymal transition in gastric cancer by inhibiting THBS2. (PMID:33206629)
• The novel role and function of LINC01235 in metastasis of gastric cancer cells by inducing epithelial-mesenchymal transition. (PMID:33771634)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.