LINC01248

Summary

LINC01248 (long intergenic non-protein coding RNA 1248, HGNC:49842) is a long non-coding RNA gene on chromosome 2p25.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49842
Approved symbol	LINC01248
Name	long intergenic non-protein coding RNA 1248
Location	2p25.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224128
Ensembl biotype	lncRNA
Entrez	102723818
RNAcentral	URS000075BE69 — lncRNA, 702 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000420221, ENST00000453678, ENST00000458264, ENST00000773893, ENST00000774014, ENST00000774015, ENST00000774016, ENST00000774017, ENST00000774018, ENST00000774019, ENST00000774020, ENST00000774021, ENST00000774022, ENST00000774023, ENST00000774024

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420221 — 3 exons

Exon	Start	End
ENSE00001776046	5684426	5684539
ENSE00004139604	5690975	5691325
ENSE00004139618	5676481	5677198

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 84.14.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6148 / max 28.3195, expressed in 203 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
26730	0.6065	200
26731	0.0083	2

Top tissues by expression

48 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.14	gold quality
cortical plate	UBERON:0005343	67.49	gold quality
ganglionic eminence	UBERON:0004023	66.25	gold quality
islet of Langerhans	UBERON:0000006	56.96	gold quality
monocyte	CL:0000576	55.36	gold quality
left testis	UBERON:0004533	53.92	gold quality
testis	UBERON:0000473	53.67	gold quality
right testis	UBERON:0004534	52.15	gold quality
prefrontal cortex	UBERON:0000451	51.90	gold quality
blood	UBERON:0000178	49.55	silver quality
lung	UBERON:0002048	47.46	gold quality
heart	UBERON:0000948	47.33	gold quality
gastrocnemius	UBERON:0001388	46.62	silver quality
nucleus accumbens	UBERON:0001882	45.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	44.85	silver quality
tibial artery	UBERON:0007610	43.45	silver quality
heart left ventricle	UBERON:0002084	43.43	gold quality
skin of leg	UBERON:0001511	43.08	gold quality
body of pancreas	UBERON:0001150	43.04	silver quality
caudate nucleus	UBERON:0001873	42.97	silver quality
stomach	UBERON:0000945	42.87	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	42.85	silver quality
putamen	UBERON:0001874	42.31	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	42.23	silver quality
lower esophagus muscularis layer	UBERON:0035833	42.03	gold quality
rectum	UBERON:0001052	42.01	gold quality
substantia nigra	UBERON:0002038	41.74	gold quality
Ammon’s horn	UBERON:0001954	41.56	gold quality
cerebral cortex	UBERON:0000956	41.33	gold quality
tibial nerve	UBERON:0001323	41.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.