LINC01257

Summary

LINC01257 (long intergenic non-protein coding RNA 1257, HGNC:26972) is a long non-coding RNA gene on chromosome 12q24.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26972
Approved symbol	LINC01257
Name	long intergenic non-protein coding RNA 1257
Location	12q24.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000204603
Ensembl biotype	lncRNA
Entrez	116437
RNAcentral	URS000075B626 — lncRNA, 2505 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000376678, ENST00000536191, ENST00000653253, ENST00000654133, ENST00000668353, ENST00000668817, ENST00000846080, ENST00000846081, ENST00000846082, ENST00000846083, ENST00000846084, ENST00000846085, ENST00000846086, ENST00000846087, ENST00000846088

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000376678 — 5 exons

Exon	Start	End
ENSE00001471324	131212205	131212931
ENSE00001471326	131209256	131210395
ENSE00001471329	131207675	131207908
ENSE00002404492	131202771	131202922
ENSE00004273518	131165004	131165230

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 75.73.

Top tissues by expression

198 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	75.73	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.86	gold quality
right hemisphere of cerebellum	UBERON:0014890	64.26	gold quality
cortical plate	UBERON:0005343	61.91	gold quality
prefrontal cortex	UBERON:0000451	59.27	gold quality
pituitary gland	UBERON:0000007	56.08	gold quality
adenohypophysis	UBERON:0002196	55.73	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.03	gold quality
ganglionic eminence	UBERON:0004023	54.60	silver quality
monocyte	CL:0000576	53.12	silver quality
frontal cortex	UBERON:0001870	52.87	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.70	gold quality
calcaneal tendon	UBERON:0003701	52.58	silver quality
Brodmann (1909) area 9	UBERON:0013540	52.52	gold quality
right lobe of liver	UBERON:0001114	52.22	gold quality
neocortex	UBERON:0001950	51.73	gold quality
right frontal lobe	UBERON:0002810	51.70	gold quality
gall bladder	UBERON:0002110	51.31	gold quality
cerebellar hemisphere	UBERON:0002245	51.17	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.66	gold quality
thyroid gland	UBERON:0002046	49.90	gold quality
left lobe of thyroid gland	UBERON:0001120	49.55	gold quality
cerebral cortex	UBERON:0000956	49.01	gold quality
apex of heart	UBERON:0002098	48.86	gold quality
anterior cingulate cortex	UBERON:0009835	48.64	gold quality
muscle of leg	UBERON:0001383	48.57	gold quality
forebrain	UBERON:0001890	48.00	gold quality
lower lobe of lung	UBERON:0008949	47.96	silver quality
primary visual cortex	UBERON:0002436	47.92	gold quality
gastrocnemius	UBERON:0001388	47.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.