LINC01259

Summary

LINC01259 (long intergenic non-protein coding RNA 1259, HGNC:49899) is a long non-coding RNA gene on chromosome 4p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49899
Approved symbol	LINC01259
Name	long intergenic non-protein coding RNA 1259
Location	4p14
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00007515
Ensembl gene	ENSG00000249667
Ensembl biotype	lncRNA
Entrez	106144599
RNAcentral	URS00004F57F4 — lncRNA, 757 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000507056, ENST00000692353, ENST00000794327, ENST00000794328, ENST00000794329, ENST00000794330

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507056 — 3 exons

Exon	Start	End
ENSE00002045374	38509767	38509947
ENSE00002061576	38517570	38518056
ENSE00002066301	38517094	38517182

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 66.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5025 / max 52.2852, expressed in 64 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
47325	0.5025	64

Top tissues by expression

75 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lymph node	UBERON:0000029	66.75	gold quality
granulocyte	CL:0000094	63.08	gold quality
ventricular zone	UBERON:0003053	62.39	gold quality
blood	UBERON:0000178	60.86	gold quality
urinary bladder	UBERON:0001255	59.57	gold quality
leukocyte	CL:0000738	58.80	gold quality
vermiform appendix	UBERON:0001154	55.86	gold quality
tonsil	UBERON:0002372	53.25	gold quality
bone marrow	UBERON:0002371	52.68	gold quality
multicellular organism	UBERON:0000468	52.22	gold quality
cortex of kidney	UBERON:0001225	51.28	gold quality
monocyte	CL:0000576	51.25	silver quality
placenta	UBERON:0001987	50.24	gold quality
body of pancreas	UBERON:0001150	48.27	gold quality
gall bladder	UBERON:0002110	47.89	gold quality
small intestine	UBERON:0002108	47.82	gold quality
small intestine Peyer’s patch	UBERON:0003454	47.74	gold quality
adult mammalian kidney	UBERON:0000082	46.69	gold quality
spleen	UBERON:0002106	46.64	gold quality
left adrenal gland cortex	UBERON:0035825	46.49	gold quality
muscle of leg	UBERON:0001383	46.41	gold quality
endometrium	UBERON:0001295	45.05	gold quality
tibial artery	UBERON:0007610	44.83	silver quality
colon	UBERON:0001155	44.74	gold quality
minor salivary gland	UBERON:0001830	44.53	gold quality
left coronary artery	UBERON:0001626	44.35	gold quality
vagina	UBERON:0000996	43.82	silver quality
gastrocnemius	UBERON:0001388	43.78	silver quality
adrenal gland	UBERON:0002369	43.61	silver quality
skin of leg	UBERON:0001511	43.32	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.75

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.