LINC01266

Summary

LINC01266 (long intergenic non-protein coding RNA 1266, HGNC:50309) is a long non-coding RNA gene on chromosome 3p26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50309
Approved symbol	LINC01266
Name	long intergenic non-protein coding RNA 1266
Location	3p26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224957
Ensembl biotype	lncRNA
Entrez	101927215
RNAcentral	URS000075AE99 — lncRNA, 3851 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000420823, ENST00000442809, ENST00000653731, ENST00000655067, ENST00000656558, ENST00000661103, ENST00000661727, ENST00000661877, ENST00000664893, ENST00000667456, ENST00000668617, ENST00000702265, ENST00000794129, ENST00000794130, ENST00000794131, ENST00000794132, ENST00000794133, ENST00000794134, ENST00000794135, ENST00000794136, ENST00000794137, ENST00000794138, ENST00000794139, ENST00000794140, ENST00000794141, ENST00000794142, ENST00000794143, ENST00000794144, ENST00000794145

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420823 — 5 exons

Exon	Start	End
ENSE00001700925	536231	536327
ENSE00001734898	592105	592183
ENSE00001761064	842376	846015
ENSE00001770500	840715	840810
ENSE00001794239	750215	750250

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 81.08.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3583 / max 82.3917, expressed in 113 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
34981	0.2097	100
34982	0.1017	18
34983	0.0469	11

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.08	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.73	gold quality
colonic epithelium	UBERON:0000397	77.77	gold quality
calcaneal tendon	UBERON:0003701	75.20	gold quality
bone marrow cell	CL:0002092	74.97	silver quality
sural nerve	UBERON:0015488	73.56	gold quality
stromal cell of endometrium	CL:0002255	67.92	gold quality
pituitary gland	UBERON:0000007	66.46	gold quality
corpus callosum	UBERON:0002336	66.37	gold quality
adenohypophysis	UBERON:0002196	65.88	gold quality
ventricular zone	UBERON:0003053	65.84	gold quality
descending thoracic aorta	UBERON:0002345	64.72	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.22	gold quality
cerebellar cortex	UBERON:0002129	64.06	gold quality
cerebellum	UBERON:0002037	64.01	gold quality
bone marrow	UBERON:0002371	64.00	silver quality
cerebellar hemisphere	UBERON:0002245	63.94	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.74	gold quality
ascending aorta	UBERON:0001496	63.61	gold quality
lower esophagus	UBERON:0013473	63.58	gold quality
lower esophagus muscularis layer	UBERON:0035833	63.56	gold quality
thoracic aorta	UBERON:0001515	63.51	gold quality
islet of Langerhans	UBERON:0000006	63.05	gold quality
right atrium auricular region	UBERON:0006631	62.71	gold quality
ganglionic eminence	UBERON:0004023	62.27	gold quality
metanephros cortex	UBERON:0010533	61.20	gold quality
cortex of kidney	UBERON:0001225	61.02	gold quality
tonsil	UBERON:0002372	61.02	gold quality
adrenal tissue	UBERON:0018303	60.56	gold quality
kidney	UBERON:0002113	60.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.