LINC01269

Summary

LINC01269 (long intergenic non-protein coding RNA 1269, HGNC:50325) is a long non-coding RNA gene on chromosome 14q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50325
Approved symbol	LINC01269
Name	long intergenic non-protein coding RNA 1269
Location	14q24.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	HNSCAT1, PARLncRNA-1, lncRNA-RP6-65G23.1
Ensembl gene	ENSG00000258689
Ensembl biotype	lncRNA
Entrez	103695436
RNAcentral	URS0000318E51 — lncRNA, 602 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000553682, ENST00000702053, ENST00000799936, ENST00000799937, ENST00000799938, ENST00000799939

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553682 — 4 exons

Exon	Start	End
ENSE00002439855	70703695	70703787
ENSE00002529459	70699995	70700200
ENSE00004188939	70698522	70698856
ENSE00004188949	70712010	70712461

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 82.88.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0936 / max 7.4293, expressed in 48 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
140411	0.0936	48

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lower esophagus mucosa	UBERON:0035834	82.88	gold quality
esophagus mucosa	UBERON:0002469	77.42	gold quality
tonsil	UBERON:0002372	74.36	gold quality
esophagus	UBERON:0001043	72.45	gold quality
ganglionic eminence	UBERON:0004023	70.15	gold quality
gall bladder	UBERON:0002110	67.79	gold quality
muscle tissue	UBERON:0002385	66.33	gold quality
sural nerve	UBERON:0015488	65.63	gold quality
vagina	UBERON:0000996	65.40	gold quality
uterine cervix	UBERON:0000002	64.55	gold quality
ectocervix	UBERON:0012249	63.77	gold quality
monocyte	CL:0000576	61.74	gold quality
leukocyte	CL:0000738	61.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.02	gold quality
blood	UBERON:0000178	60.23	gold quality
islet of Langerhans	UBERON:0000006	59.04	gold quality
minor salivary gland	UBERON:0001830	58.20	gold quality
saliva-secreting gland	UBERON:0001044	58.10	gold quality
lymph node	UBERON:0000029	56.28	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	55.64	gold quality
body of stomach	UBERON:0001161	54.64	gold quality
stomach	UBERON:0000945	54.25	gold quality
bone marrow	UBERON:0002371	53.61	gold quality
duodenum	UBERON:0002114	53.14	gold quality
adult mammalian kidney	UBERON:0000082	53.03	gold quality
granulocyte	CL:0000094	52.92	gold quality
prefrontal cortex	UBERON:0000451	52.43	gold quality
vermiform appendix	UBERON:0001154	52.36	gold quality
multicellular organism	UBERON:0000468	50.97	gold quality
urinary bladder	UBERON:0001255	50.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.