LINC01273

Summary

LINC01273 (long intergenic non-protein coding RNA 1273, HGNC:50329) is a long non-coding RNA gene on chromosome 20q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50329
Approved symbol	LINC01273
Name	long intergenic non-protein coding RNA 1273
Location	20q13.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231742
Ensembl biotype	lncRNA
Entrez	101927541
RNAcentral	URS000075BD89 — lncRNA, 705 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000411453, ENST00000427333, ENST00000444478, ENST00000659473, ENST00000661469, ENST00000664618, ENST00000665536, ENST00000668708, ENST00000670659, ENST00000716893, ENST00000716894, ENST00000769179, ENST00000769180, ENST00000769181, ENST00000769182, ENST00000769183, ENST00000769184, ENST00000769185, ENST00000769186, ENST00000769187, ENST00000769188, ENST00000769189, ENST00000769190, ENST00000769191, ENST00000769192

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411453 — 3 exons

Exon	Start	End
ENSE00001772198	50172923	50173017
ENSE00004130078	50176281	50176677
ENSE00004130084	50172468	50172788

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 84.04.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4447 / max 54.2742, expressed in 213 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185203	0.2803	116
185204	0.1644	71

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.04	gold quality
apex of heart	UBERON:0002098	74.83	gold quality
sural nerve	UBERON:0015488	70.97	gold quality
colonic epithelium	UBERON:0000397	70.91	silver quality
heart left ventricle	UBERON:0002084	69.72	gold quality
left adrenal gland cortex	UBERON:0035825	69.62	gold quality
gastrocnemius	UBERON:0001388	68.95	gold quality
right adrenal gland	UBERON:0001233	68.90	gold quality
right adrenal gland cortex	UBERON:0035827	68.85	gold quality
left adrenal gland	UBERON:0001234	68.82	gold quality
muscle of leg	UBERON:0001383	68.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	68.28	gold quality
ventricular zone	UBERON:0003053	67.63	gold quality
left ovary	UBERON:0002119	67.54	gold quality
skeletal muscle tissue	UBERON:0001134	67.20	gold quality
heart	UBERON:0000948	67.10	gold quality
adrenal gland	UBERON:0002369	67.05	gold quality
ovary	UBERON:0000992	66.84	gold quality
lower esophagus muscularis layer	UBERON:0035833	66.35	gold quality
lower esophagus	UBERON:0013473	66.29	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.10	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.07	gold quality
right uterine tube	UBERON:0001302	65.93	gold quality
adenohypophysis	UBERON:0002196	65.85	gold quality
right lobe of thyroid gland	UBERON:0001119	65.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.79	gold quality
popliteal artery	UBERON:0002250	65.77	gold quality
tibial artery	UBERON:0007610	65.75	gold quality
muscle layer of sigmoid colon	UBERON:0035805	65.47	gold quality
right atrium auricular region	UBERON:0006631	65.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.87

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long intergenic non-protein coding RNA 1273 confers sorafenib resistance in hepatocellular carcinoma via regulation of methyltransferase 3. (PMID:35037556)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.