LINC01281

Summary

LINC01281 (long intergenic non-protein coding RNA 1281, HGNC:50337) is a long non-coding RNA gene on chromosome Xp11.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50337
Approved symbol	LINC01281
Name	long intergenic non-protein coding RNA 1281
Location	Xp11.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235304
Ensembl biotype	lncRNA
Entrez	286442
RNAcentral	URS00005DB5CD — lncRNA, 1773 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000429281, ENST00000448597, ENST00000655040, ENST00000760290, ENST00000760291, ENST00000760292

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429281 — 2 exons

Exon	Start	End
ENSE00001609816	39327223	39327361
ENSE00001681417	39305634	39306167

Expression profiles

Bgee: expression breadth broad, 70 present calls, max score 70.33.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3093 / max 126.5823, expressed in 45 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
198915	0.1451	30
198914	0.0764	19
198912	0.0624	21
198913	0.0253	7

Top tissues by expression

70 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	70.33	gold quality
lymph node	UBERON:0000029	68.62	gold quality
kidney	UBERON:0002113	62.77	silver quality
sural nerve	UBERON:0015488	61.87	silver quality
muscle tissue	UBERON:0002385	60.72	silver quality
anterior cingulate cortex	UBERON:0009835	59.23	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.16	gold quality
vermiform appendix	UBERON:0001154	58.71	gold quality
prefrontal cortex	UBERON:0000451	57.29	gold quality
ganglionic eminence	UBERON:0004023	55.69	silver quality
saliva-secreting gland	UBERON:0001044	55.42	gold quality
urinary bladder	UBERON:0001255	54.81	gold quality
blood	UBERON:0000178	53.32	gold quality
small intestine	UBERON:0002108	52.16	gold quality
small intestine Peyer’s patch	UBERON:0003454	51.99	gold quality
leukocyte	CL:0000738	51.41	silver quality
myometrium	UBERON:0001296	50.28	gold quality
intestine	UBERON:0000160	49.83	gold quality
islet of Langerhans	UBERON:0000006	49.70	silver quality
gall bladder	UBERON:0002110	49.27	gold quality
multicellular organism	UBERON:0000468	48.53	gold quality
upper lobe of left lung	UBERON:0008952	47.54	gold quality
lung	UBERON:0002048	47.51	gold quality
colon	UBERON:0001155	47.07	gold quality
muscle of leg	UBERON:0001383	46.88	gold quality
tibial nerve	UBERON:0001323	46.74	silver quality
granulocyte	CL:0000094	46.68	silver quality
heart left ventricle	UBERON:0002084	45.99	silver quality
tibial artery	UBERON:0007610	45.80	gold quality
gastrocnemius	UBERON:0001388	45.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.