LINC01288

Summary

LINC01288 (long intergenic non-protein coding RNA 1288, HGNC:50353) is a long non-coding RNA gene on chromosome 8p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50353
Approved symbol	LINC01288
Name	long intergenic non-protein coding RNA 1288
Location	8p12
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00014671
Ensembl gene	ENSG00000254344
Ensembl biotype	lncRNA
Entrez	103689844
RNAcentral	URS00007E4BFB — lncRNA, 660 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000519189, ENST00000648617, ENST00000809662

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000519189 — 4 exons

Exon	Start	End
ENSE00002095401	34792758	34792965
ENSE00002101325	34819272	34819405
ENSE00002105970	34784028	34784096
ENSE00002131670	34864657	34865364

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 83.69.

Top tissues by expression

47 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.69	gold quality
prefrontal cortex	UBERON:0000451	53.89	gold quality
blood	UBERON:0000178	49.98	silver quality
monocyte	CL:0000576	49.77	silver quality
liver	UBERON:0002107	49.72	silver quality
lymph node	UBERON:0000029	49.50	gold quality
islet of Langerhans	UBERON:0000006	48.46	silver quality
bone marrow	UBERON:0002371	47.36	silver quality
gastrocnemius	UBERON:0001388	45.44	silver quality
skin of leg	UBERON:0001511	45.29	silver quality
ascending aorta	UBERON:0001496	44.09	silver quality
heart	UBERON:0000948	43.28	silver quality
heart left ventricle	UBERON:0002084	42.73	silver quality
thoracic aorta	UBERON:0001515	42.30	silver quality
adult mammalian kidney	UBERON:0000082	42.15	silver quality
multicellular organism	UBERON:0000468	41.32	gold quality
urinary bladder	UBERON:0001255	41.28	silver quality
tibial artery	UBERON:0007610	41.17	silver quality
subcutaneous adipose tissue	UBERON:0002190	40.67	silver quality
lower esophagus muscularis layer	UBERON:0035833	40.66	silver quality
adipose tissue	UBERON:0001013	40.56	silver quality
prostate gland	UBERON:0002367	40.21	silver quality
thoracic mammary gland	UBERON:0005200	40.13	silver quality
skin of abdomen	UBERON:0001416	39.64	silver quality
descending thoracic aorta	UBERON:0002345	39.55	silver quality
anterior cingulate cortex	UBERON:0009835	39.47	silver quality
muscle layer of sigmoid colon	UBERON:0035805	39.45	silver quality
body of stomach	UBERON:0001161	39.37	silver quality
testis	UBERON:0000473	38.97	gold quality
body of uterus	UBERON:0009853	38.97	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.91

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• data have demonstrated that LINC01288 serves as a crucial mediator of IL-6/STAT3 pathway and created novel interplay between lncRNAs and tumor development (PMID:31054777)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.