LINC01320

Summary

LINC01320 (long intergenic non-protein coding RNA 1320, HGNC:50526) is a long non-coding RNA gene on chromosome 2p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50526
Approved symbol	LINC01320
Name	long intergenic non-protein coding RNA 1320
Location	2p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228262
Ensembl biotype	lncRNA
Entrez	104355288
RNAcentral	URS00007E4B64 — lncRNA, 1131 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 57 — 57 lncRNA

ENST00000366209, ENST00000422558, ENST00000423663, ENST00000442026, ENST00000453774, ENST00000587085, ENST00000603129, ENST00000604250, ENST00000607437, ENST00000616475, ENST00000621006, ENST00000625995, ENST00000626008, ENST00000626601, ENST00000626688, ENST00000627270, ENST00000627935, ENST00000628407, ENST00000630686, ENST00000650021, ENST00000654103, ENST00000658168, ENST00000659537, ENST00000661209, ENST00000664138, ENST00000664286, ENST00000664777, ENST00000665109, ENST00000666112, ENST00000666399, ENST00000667658, ENST00000671252, ENST00000671333, ENST00000671356, ENST00000701733, ENST00000771863, ENST00000771864, ENST00000771865, ENST00000771866, ENST00000771867, ENST00000771868, ENST00000771869, ENST00000771870, ENST00000771871, ENST00000771872, ENST00000771873, ENST00000771874, ENST00000771875, ENST00000771876, ENST00000771877, ENST00000835701, ENST00000835702, ENST00000835703, ENST00000835704, ENST00000835705, ENST00000835706, ENST00000835707

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000366209 — 6 exons

Exon	Start	End
ENSE00001441159	34297468	34297753
ENSE00001594016	33855688	33855753
ENSE00001657671	34286643	34286746
ENSE00001666431	33706886	33706953
ENSE00001701299	33944428	33944553
ENSE00001733506	33926840	33926968

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 96.16.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2567 / max 181.8701, expressed in 31 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
19700	0.1536	18
19702	0.0687	14
202153	0.0108	4
19704	0.0103	6
202154	0.0078	2
19701	0.0056	3

Top tissues by expression

137 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
metanephros cortex	UBERON:0010533	96.16	gold quality
adult mammalian kidney	UBERON:0000082	94.90	gold quality
kidney	UBERON:0002113	91.83	gold quality
endometrium	UBERON:0001295	91.04	gold quality
cortex of kidney	UBERON:0001225	87.03	gold quality
right uterine tube	UBERON:0001302	86.93	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.14	gold quality
thymus	UBERON:0002370	83.94	silver quality
quadriceps femoris	UBERON:0001377	83.49	gold quality
cerebellar vermis	UBERON:0004720	80.25	gold quality
fallopian tube	UBERON:0003889	76.96	gold quality
liver	UBERON:0002107	76.47	gold quality
right lobe of liver	UBERON:0001114	75.32	gold quality
body of pancreas	UBERON:0001150	75.22	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.18	gold quality
pancreas	UBERON:0001264	70.78	gold quality
colonic epithelium	UBERON:0000397	70.28	silver quality
testis	UBERON:0000473	69.31	gold quality
bone marrow cell	CL:0002092	68.98	silver quality
endocervix	UBERON:0000458	67.79	gold quality
gall bladder	UBERON:0002110	67.32	gold quality
right testis	UBERON:0004534	67.22	gold quality
left uterine tube	UBERON:0001303	66.80	gold quality
left testis	UBERON:0004533	66.75	gold quality
sural nerve	UBERON:0015488	66.16	gold quality
cortical plate	UBERON:0005343	62.45	gold quality
skeletal muscle tissue	UBERON:0001134	61.78	gold quality
placenta	UBERON:0001987	61.33	gold quality
islet of Langerhans	UBERON:0000006	61.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.83	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-10287	yes	30.92
E-ANND-3	yes	6.04

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• N6-methyladenosine (m6A)-mediated up-regulation of long noncoding RNA LINC01320 promotes the proliferation, migration, and invasion of gastric cancer via miR495-5p/RAB19 axis. (PMID:34288797)
• Effects of lncRNA LINC01320 on Proliferation and Migration of Pancreatic Cancer Cells through Targeted Regulation of miR-324-3p. (PMID:34976325)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.