LINC01348

Summary

LINC01348 (long intergenic non-protein coding RNA 1348, HGNC:50567) is a long non-coding RNA gene on chromosome 1q42.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50567
Approved symbol	LINC01348
Name	long intergenic non-protein coding RNA 1348
Location	1q42.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000280587
Ensembl biotype	lncRNA
Entrez	731656
RNAcentral	URS000075E04B — lncRNA, 1000 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 46 — 46 lncRNA

ENST00000628622, ENST00000687230, ENST00000687433, ENST00000687678, ENST00000688791, ENST00000690081, ENST00000690660, ENST00000701981, ENST00000702703, ENST00000702857, ENST00000723715, ENST00000723716, ENST00000723717, ENST00000723718, ENST00000723719, ENST00000723720, ENST00000723721, ENST00000723722, ENST00000723723, ENST00000723724, ENST00000723725, ENST00000723726, ENST00000723727, ENST00000723728, ENST00000723729, ENST00000723730, ENST00000723731, ENST00000723732, ENST00000723733, ENST00000723734, ENST00000723735, ENST00000723736, ENST00000723737, ENST00000723738, ENST00000723739, ENST00000723740, ENST00000723741, ENST00000723742, ENST00000723743, ENST00000723744, ENST00000723745, ENST00000723746, ENST00000723747, ENST00000723748, ENST00000723749, ENST00000836061

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000628622 — 3 exons

Exon	Start	End
ENSE00003760544	235074103	235074220
ENSE00003761906	235065479	235065616
ENSE00003772316	235067305	235070310

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 90.58.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5922 / max 194.9071, expressed in 89 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
201999	0.5152	64
201998	0.0634	21
201997	0.0137	6

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	90.58	gold quality
right lobe of liver	UBERON:0001114	90.14	gold quality
duodenum	UBERON:0002114	63.69	gold quality
skeletal muscle tissue	UBERON:0001134	59.37	silver quality
omental fat pad	UBERON:0010414	58.93	gold quality
skin of leg	UBERON:0001511	57.95	gold quality
zone of skin	UBERON:0000014	57.69	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.40	gold quality
skin of abdomen	UBERON:0001416	57.20	gold quality
small intestine	UBERON:0002108	54.19	gold quality
transverse colon	UBERON:0001157	54.05	gold quality
saliva-secreting gland	UBERON:0001044	53.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.46	gold quality
minor salivary gland	UBERON:0001830	53.42	gold quality
right ovary	UBERON:0002118	53.34	gold quality
bone marrow	UBERON:0002371	53.24	gold quality
blood	UBERON:0000178	53.16	gold quality
intestine	UBERON:0000160	53.14	gold quality
small intestine Peyer’s patch	UBERON:0003454	53.11	gold quality
adipose tissue	UBERON:0001013	52.99	gold quality
descending thoracic aorta	UBERON:0002345	52.98	gold quality
colon	UBERON:0001155	52.40	gold quality
mucosa of transverse colon	UBERON:0004991	52.22	gold quality
body of stomach	UBERON:0001161	51.91	gold quality
spleen	UBERON:0002106	51.79	gold quality
multicellular organism	UBERON:0000468	51.45	gold quality
stomach	UBERON:0000945	51.41	gold quality
gall bladder	UBERON:0002110	51.40	gold quality
right lobe of thyroid gland	UBERON:0001119	51.37	gold quality
rectum	UBERON:0001052	51.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.67

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing. (PMID:34140643)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.