LINC01355

Summary

LINC01355 (long intergenic non-protein coding RNA 1355, HGNC:50584) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50584
Approved symbol	LINC01355
Name	long intergenic non-protein coding RNA 1355
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Aliases	HYPAL
Ensembl gene	ENSG00000261326
Ensembl biotype	lncRNA
Entrez	100996511
RNAcentral	URS000075ED94 — lncRNA, 3527 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000566551, ENST00000604481, ENST00000647667, ENST00000655082, ENST00000660265

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000566551 — 1 exons

Exon	Start	End
ENSE00002595853	23281309	23286752

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 84.77.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	84.77	gold quality
endometrium	UBERON:0001295	83.29	gold quality
lower esophagus mucosa	UBERON:0035834	81.32	gold quality
endocervix	UBERON:0000458	81.12	gold quality
left lobe of thyroid gland	UBERON:0001120	80.89	gold quality
left ovary	UBERON:0002119	80.69	gold quality
thyroid gland	UBERON:0002046	80.54	gold quality
right ovary	UBERON:0002118	80.53	gold quality
right lobe of thyroid gland	UBERON:0001119	80.52	gold quality
tibial nerve	UBERON:0001323	80.48	gold quality
body of uterus	UBERON:0009853	80.01	gold quality
ovary	UBERON:0000992	79.93	gold quality
prostate gland	UBERON:0002367	79.85	gold quality
pituitary gland	UBERON:0000007	79.47	gold quality
uterine cervix	UBERON:0000002	79.20	gold quality
myometrium	UBERON:0001296	79.16	gold quality
adenohypophysis	UBERON:0002196	78.97	gold quality
muscle layer of sigmoid colon	UBERON:0035805	78.32	gold quality
body of pancreas	UBERON:0001150	78.11	gold quality
cerebellar hemisphere	UBERON:0002245	78.02	gold quality
ectocervix	UBERON:0012249	78.00	gold quality
cerebellar cortex	UBERON:0002129	77.91	gold quality
vagina	UBERON:0000996	77.67	gold quality
cerebellum	UBERON:0002037	77.67	gold quality
right hemisphere of cerebellum	UBERON:0014890	77.61	gold quality
minor salivary gland	UBERON:0001830	77.33	gold quality
right coronary artery	UBERON:0001625	77.32	gold quality
colonic epithelium	UBERON:0000397	76.84	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.81	gold quality
saliva-secreting gland	UBERON:0001044	76.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.52

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01355 Contributes to Malignant Phenotype of Oral Squamous Cell Carcinoma and Cytotoxic T Cell Infiltration via Activating Notch Signaling Pathway. (PMID:34355042)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.