LINC01372

Summary

LINC01372 (long intergenic non-protein coding RNA 1372, HGNC:50623) is a long non-coding RNA gene on chromosome 7q11.21.

At a glance

• GWAS associations: 1
• Clinical variants (ClinVar): 1 total

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50623
Approved symbol	LINC01372
Name	long intergenic non-protein coding RNA 1372
Location	7q11.21
Locus type	RNA, long non-coding
Status	Approved
Entrez	101929736
RNAcentral	URS000075C35E — lncRNA, 515 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

1 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	1
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000037810 (7:67335669 A>G), RS1000410235 (7:67335970 C>T), RS1001173717 (7:67336071 G>A), RS1001434897 (7:67336423 A>G), RS1003516348 (7:67337688 A>G), RS1004171729 (7:67339581 T>A,C), RS1004547716 (7:67339608 C>T), RS1004963191 (7:67338881 C>T), RS1004999526 (7:67338636 G>A), RS1005481167 (7:67334640 A>G), RS1005513715 (7:67334275 T>C), RS1006975660 (7:67335579 C>T), RS1007979814 (7:67337087 T>C), RS1008012430 (7:67336820 T>C), RS1008626348 (7:67340440 C>T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

1 associations (top):

Study	Trait	p-value
GCST012115_3	Rheumatic heart disease	4.000000e-07

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Triclosan	decreases expression	1
Cadmium Chloride	decreases expression	1
Lactic Acid	affects expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.