LINC01377

Summary

LINC01377 (long intergenic non-protein coding RNA 1377, HGNC:50642) is a long non-coding RNA gene on chromosome 5p15.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50642
Approved symbol	LINC01377
Name	long intergenic non-protein coding RNA 1377
Location	5p15.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249808
Ensembl biotype	lncRNA
Entrez	102467074
RNAcentral	URS000075DF96 — lncRNA, 649 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000505396, ENST00000652864, ENST00000692105

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505396 — 2 exons

Exon	Start	End
ENSE00004263256	3177792	3178179
ENSE00004263257	3180929	3181489

Expression profiles

Bgee: expression breadth broad, 59 present calls, max score 95.20.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0453 / max 35.1846, expressed in 4 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55602	0.0270	4
55601	0.0184	3

Top tissues by expression

67 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.20	gold quality
liver	UBERON:0002107	91.14	silver quality
thymus	UBERON:0002370	90.11	silver quality
bone marrow	UBERON:0002371	89.59	silver quality
spleen	UBERON:0002106	87.35	silver quality
lung	UBERON:0002048	86.60	silver quality
skeletal muscle tissue	UBERON:0001134	86.02	silver quality
left testis	UBERON:0004533	80.78	gold quality
testis	UBERON:0000473	80.55	gold quality
right testis	UBERON:0004534	79.77	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
sural nerve	UBERON:0015488	65.88	silver quality
subcutaneous adipose tissue	UBERON:0002190	64.51	gold quality
tibial nerve	UBERON:0001323	63.83	gold quality
multicellular organism	UBERON:0000468	61.75	gold quality
prefrontal cortex	UBERON:0000451	57.53	gold quality
right hemisphere of cerebellum	UBERON:0014890	55.92	gold quality
blood	UBERON:0000178	55.78	gold quality
cerebellum	UBERON:0002037	55.59	gold quality
cerebellar cortex	UBERON:0002129	55.42	gold quality
cerebellar hemisphere	UBERON:0002245	55.40	gold quality
monocyte	CL:0000576	53.51	gold quality
spinal cord	UBERON:0002240	53.36	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.28	gold quality
brain	UBERON:0000955	51.83	gold quality
small intestine	UBERON:0002108	50.96	gold quality
skin of leg	UBERON:0001511	50.84	gold quality
frontal cortex	UBERON:0001870	49.77	silver quality
islet of Langerhans	UBERON:0000006	49.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.