LINC01378

Summary

LINC01378 (long intergenic non-protein coding RNA 1378, HGNC:50645) is a long non-coding RNA gene on chromosome 4q26.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50645
Approved symbol	LINC01378
Name	long intergenic non-protein coding RNA 1378
Location	4q26
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236922
Ensembl biotype	lncRNA
Entrez	103689918
RNAcentral	URS00007E4A54 — lncRNA, 429 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 81 — 81 lncRNA

ENST00000419264, ENST00000420701, ENST00000422145, ENST00000426240, ENST00000437514, ENST00000448804, ENST00000600624, ENST00000608048, ENST00000615833, ENST00000626258, ENST00000630321, ENST00000654527, ENST00000654670, ENST00000655627, ENST00000655906, ENST00000656442, ENST00000656637, ENST00000658771, ENST00000659910, ENST00000660654, ENST00000662639, ENST00000662705, ENST00000664454, ENST00000665215, ENST00000665403, ENST00000665422, ENST00000666918, ENST00000667115, ENST00000667220, ENST00000667741, ENST00000668162, ENST00000668339, ENST00000668361, ENST00000668756, ENST00000669946, ENST00000670348, ENST00000670630, ENST00000671002, ENST00000671671, ENST00000690735, ENST00000717499, ENST00000717500, ENST00000717501, ENST00000717502, ENST00000717503, ENST00000717504, ENST00000717505, ENST00000717555, ENST00000717556, ENST00000717557, ENST00000717558, ENST00000717559, ENST00000717599, ENST00000717600, ENST00000717601, ENST00000717602, ENST00000717603, ENST00000717604, ENST00000717605, ENST00000717606, ENST00000717607, ENST00000717608, ENST00000717609, ENST00000717610, ENST00000717611, ENST00000717637, ENST00000717638, ENST00000717639, ENST00000717640, ENST00000717641, ENST00000717642, ENST00000717643, ENST00000717644, ENST00000717645, ENST00000717646, ENST00000717647, ENST00000828265, ENST00000828266, ENST00000828267, ENST00000828268, ENST00000828269

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419264 — 4 exons

Exon	Start	End
ENSE00001755908	117371592	117371662
ENSE00001799080	117372364	117372471
ENSE00004032916	117361306	117361506
ENSE00004240877	117372596	117372850

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 80.93.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0795 / max 11.7643, expressed in 32 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
49412	0.0795	32

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superior frontal gyrus	UBERON:0002661	80.93	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.59	silver quality
Brodmann (1909) area 9	UBERON:0013540	73.65	gold quality
right frontal lobe	UBERON:0002810	73.24	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	72.45	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.98	gold quality
frontal cortex	UBERON:0001870	70.53	gold quality
bone marrow cell	CL:0002092	69.17	silver quality
primary visual cortex	UBERON:0002436	68.44	gold quality
cerebral cortex	UBERON:0000956	68.34	gold quality
prefrontal cortex	UBERON:0000451	67.89	gold quality
anterior cingulate cortex	UBERON:0009835	67.28	gold quality
ganglionic eminence	UBERON:0004023	64.23	gold quality
corpus callosum	UBERON:0002336	62.99	gold quality
colonic epithelium	UBERON:0000397	62.40	silver quality
brain	UBERON:0000955	61.17	gold quality
caudate nucleus	UBERON:0001873	60.19	gold quality
putamen	UBERON:0001874	59.44	gold quality
sural nerve	UBERON:0015488	58.95	silver quality
bone marrow	UBERON:0002371	57.87	silver quality
stromal cell of endometrium	CL:0002255	57.09	gold quality
nucleus accumbens	UBERON:0001882	54.14	gold quality
blood	UBERON:0000178	53.25	gold quality
monocyte	CL:0000576	53.16	silver quality
lymph node	UBERON:0000029	52.01	gold quality
muscle of leg	UBERON:0001383	50.99	gold quality
duodenum	UBERON:0002114	50.99	gold quality
gastrocnemius	UBERON:0001388	50.76	gold quality
adult mammalian kidney	UBERON:0000082	50.63	gold quality
kidney	UBERON:0002113	50.54	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-35	yes	98.92
E-ANND-3	yes	4.51

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.