LINC01389
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Summary
LINC01389 (long intergenic non-protein coding RNA 1389, HGNC:50661) is a long non-coding RNA gene on chromosome 1p33.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:50661 |
| Approved symbol | LINC01389 |
| Name | long intergenic non-protein coding RNA 1389 |
| Location | 1p33 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000225762 |
| Ensembl biotype | lncRNA |
| Entrez | 102724077 |
| RNAcentral | URS00007E3818 — lncRNA, 869 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 11 — 11 lncRNA
ENST00000420876, ENST00000828805, ENST00000828806, ENST00000828807, ENST00000828808, ENST00000828809, ENST00000828810, ENST00000828811, ENST00000828812, ENST00000828813, ENST00000828814
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000420876 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001642433 | 47380928 | 47381143 |
| ENSE00001735913 | 47386248 | 47386356 |
| ENSE00001784857 | 47408320 | 47408477 |
Expression profiles
Bgee: expression breadth ubiquitous, 130 present calls, max score 88.31.
FANTOM5 (CAGE): breadth broad, TPM avg 1.9723 / max 54.2742, expressed in 831 samples.
FANTOM5 promoters (3 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 12238 | 1.7693 | 802 |
| 12237 | 0.1161 | 28 |
| 12236 | 0.0869 | 27 |
Top tissues by expression
130 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 88.31 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 85.25 | gold quality |
| mucosa of transverse colon | UBERON:0004991 | 84.34 | gold quality |
| colonic epithelium | UBERON:0000397 | 77.44 | gold quality |
| rectum | UBERON:0001052 | 75.41 | gold quality |
| sural nerve | UBERON:0015488 | 71.70 | gold quality |
| transverse colon | UBERON:0001157 | 71.31 | gold quality |
| ganglionic eminence | UBERON:0004023 | 70.44 | gold quality |
| right testis | UBERON:0004534 | 67.97 | gold quality |
| cortical plate | UBERON:0005343 | 67.51 | gold quality |
| monocyte | CL:0000576 | 67.25 | gold quality |
| left testis | UBERON:0004533 | 67.06 | gold quality |
| ventricular zone | UBERON:0003053 | 66.99 | gold quality |
| leukocyte | CL:0000738 | 66.82 | gold quality |
| testis | UBERON:0000473 | 66.42 | gold quality |
| stromal cell of endometrium | CL:0002255 | 66.15 | gold quality |
| mucosa of stomach | UBERON:0001199 | 65.41 | gold quality |
| endometrium | UBERON:0001295 | 65.32 | gold quality |
| colon | UBERON:0001155 | 65.13 | gold quality |
| tibial nerve | UBERON:0001323 | 64.39 | gold quality |
| cerebellar cortex | UBERON:0002129 | 64.29 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 64.26 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 64.25 | gold quality |
| intestine | UBERON:0000160 | 64.10 | gold quality |
| cerebellum | UBERON:0002037 | 64.09 | gold quality |
| right lobe of liver | UBERON:0001114 | 62.95 | gold quality |
| lymph node | UBERON:0000029 | 62.80 | gold quality |
| liver | UBERON:0002107 | 62.57 | gold quality |
| right hemisphere of cerebellum | UBERON:0014890 | 62.43 | gold quality |
| tibial artery | UBERON:0007610 | 62.40 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 2.08 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): anterior segment dysgenesis, aortic aneurysm, familial thoracic 1, aortic aneurysm, familial thoracic 11, susceptibility to, cataract 34 multiple types, congenital primary aphakia, familial thoracic aortic aneurysm and aortic dissection