LINC01414

Summary

LINC01414 (long intergenic non-protein coding RNA 1414, HGNC:50707) is a long non-coding RNA gene on chromosome 8q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50707
Approved symbol	LINC01414
Name	long intergenic non-protein coding RNA 1414
Location	8q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253554
Ensembl biotype	lncRNA
Entrez	102724623
RNAcentral	URS000055A7F8 — lncRNA, 579 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000520365, ENST00000521958, ENST00000523191, ENST00000524360, ENST00000648669, ENST00000665620, ENST00000668083, ENST00000668525, ENST00000726321, ENST00000726322, ENST00000726323, ENST00000726324, ENST00000726325, ENST00000726326, ENST00000726327, ENST00000726328, ENST00000726329, ENST00000726330, ENST00000726331, ENST00000726332, ENST00000726333, ENST00000737825, ENST00000737826, ENST00000737827, ENST00000737828, ENST00000737829, ENST00000792678, ENST00000792679, ENST00000792680

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000520365 — 3 exons

Exon	Start	End
ENSE00002120663	64230556	64230616
ENSE00002124734	64239834	64240282
ENSE00002131446	64151106	64151164

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 84.39.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 1.3084 / max 631.1291, expressed in 113 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
93335	1.0177	91
93334	0.2907	65

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.01	gold quality
colonic epithelium	UBERON:0000397	77.95	gold quality
bone marrow cell	CL:0002092	71.04	gold quality
superior frontal gyrus	UBERON:0002661	66.27	gold quality
cortical plate	UBERON:0005343	65.60	gold quality
primary visual cortex	UBERON:0002436	65.55	gold quality
prefrontal cortex	UBERON:0000451	65.49	gold quality
ventricular zone	UBERON:0003053	64.86	gold quality
frontal cortex	UBERON:0001870	63.28	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.89	gold quality
ganglionic eminence	UBERON:0004023	62.04	gold quality
cerebral cortex	UBERON:0000956	61.26	gold quality
Brodmann (1909) area 9	UBERON:0013540	61.15	gold quality
anterior cingulate cortex	UBERON:0009835	59.94	gold quality
right frontal lobe	UBERON:0002810	59.37	gold quality
substantia nigra	UBERON:0002038	59.00	gold quality
brain	UBERON:0000955	56.97	gold quality
monocyte	CL:0000576	55.57	gold quality
amygdala	UBERON:0001876	55.35	gold quality
putamen	UBERON:0001874	54.63	gold quality
right ovary	UBERON:0002118	54.54	gold quality
gall bladder	UBERON:0002110	54.45	gold quality
hypothalamus	UBERON:0001898	53.92	gold quality
caudate nucleus	UBERON:0001873	52.47	gold quality
nucleus accumbens	UBERON:0001882	52.39	gold quality
blood	UBERON:0000178	51.35	gold quality
placenta	UBERON:0001987	50.55	gold quality
Ammon’s horn	UBERON:0001954	49.98	gold quality
muscle of leg	UBERON:0001383	49.82	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-35	yes	58.88
E-ANND-3	yes	4.16

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01414/LINC00824 genetic polymorphisms in association with the susceptibility of chronic obstructive pulmonary disease. (PMID:34233676)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.