LINC01419

Summary

LINC01419 (long intergenic non-protein coding RNA 1419, HGNC:50712) is a long non-coding RNA gene on chromosome 8q21.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50712
Approved symbol	LINC01419
Name	long intergenic non-protein coding RNA 1419
Location	8q21.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00014497, PRLH1
Ensembl gene	ENSG00000253898
Ensembl biotype	lncRNA
Entrez	103352670
RNAcentral	URS00001A8BAE — lncRNA, 1521 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000522365

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000522365 — 2 exons

Exon	Start	End
ENSE00004279496	83407692	83408900
ENSE00004279497	83403739	83404069

Expression profiles

Bgee: expression breadth broad, 32 present calls, max score 87.15.

Top tissues by expression

164 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.15	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.77	gold quality
leukocyte	CL:0000738	55.78	gold quality
monocyte	CL:0000576	55.75	gold quality
cortex of kidney	UBERON:0001225	46.52	silver quality
tibial artery	UBERON:0007610	45.02	silver quality
body of pancreas	UBERON:0001150	44.71	silver quality
islet of Langerhans	UBERON:0000006	44.60	silver quality
tibial nerve	UBERON:0001323	43.74	silver quality
gastrocnemius	UBERON:0001388	43.73	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
aorta	UBERON:0000947	42.67	silver quality
secondary oocyte	CL:0000655	42.57	gold quality
right atrium auricular region	UBERON:0006631	41.43	silver quality
vastus lateralis	UBERON:0001379	41.41	gold quality
vagina	UBERON:0000996	41.38	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
prefrontal cortex	UBERON:0000451	41.35	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
oviduct epithelium	UBERON:0004804	41.33	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality
fallopian tube	UBERON:0003889	40.92	gold quality
urinary bladder	UBERON:0001255	40.88	gold quality
amniotic fluid	UBERON:0000173	40.69	gold quality
nasal cavity mucosa	UBERON:0001826	40.63	gold quality
jejunal mucosa	UBERON:0000399	40.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 5)

• LINC01419 exhibited oncogenic behavior in lung adenocarcinoma via binding to miR-519b-3p to enhance the expression of RCCD1 (PMID:31582214)
• LINC01419 promotes cell proliferation and metastasis in hepatocellular carcinoma by enhancing NDRG1 promoter activity. (PMID:32557341)
• LINC01419-mediated epigenetic silencing of ZIC1 promotes metastasis in hepatocellular carcinoma through the PI3K/Akt signaling pathway. (PMID:33772101)
• LINC01419 Promotes the Proliferation of Hepatoma Cells by Recruiting XRCC5 and Regulating Its Phosphorylation to Repair DNA Damage. (PMID:35903292)
• The role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting EZH2 and regulating FBP1 expression. (PMID:36050791)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.