LINC01423

Summary

LINC01423 (long intergenic non-protein coding RNA 1423, HGNC:50732) is a long non-coding RNA gene on chromosome 21q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50732
Approved symbol	LINC01423
Name	long intergenic non-protein coding RNA 1423
Location	21q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231231
Ensembl biotype	lncRNA
Entrez	102724678
RNAcentral	URS000075C33E — lncRNA, 621 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000414189, ENST00000436845

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414189 — 5 exons

Exon	Start	End
ENSE00001595871	38332962	38333032
ENSE00001639894	38323635	38323898
ENSE00001668823	38333316	38333364
ENSE00001671015	38332426	38332477
ENSE00001784646	38325783	38325954

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 84.29.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4737 / max 45.9858, expressed in 94 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
190451	0.2563	71
190453	0.1403	52
190452	0.0771	43

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.29	gold quality
right lung	UBERON:0002167	68.25	gold quality
descending thoracic aorta	UBERON:0002345	66.02	gold quality
sural nerve	UBERON:0015488	65.40	gold quality
lymph node	UBERON:0000029	64.85	gold quality
calcaneal tendon	UBERON:0003701	62.50	gold quality
ascending aorta	UBERON:0001496	62.13	gold quality
thyroid gland	UBERON:0002046	62.04	gold quality
thoracic aorta	UBERON:0001515	62.02	gold quality
left lobe of thyroid gland	UBERON:0001120	61.36	gold quality
popliteal artery	UBERON:0002250	61.25	gold quality
tibial artery	UBERON:0007610	61.22	gold quality
monocyte	CL:0000576	58.56	gold quality
blood	UBERON:0000178	56.93	gold quality
vermiform appendix	UBERON:0001154	56.90	gold quality
metanephros cortex	UBERON:0010533	56.75	gold quality
cortex of kidney	UBERON:0001225	56.11	gold quality
right lobe of thyroid gland	UBERON:0001119	55.73	gold quality
superior frontal gyrus	UBERON:0002661	55.22	gold quality
islet of Langerhans	UBERON:0000006	54.99	gold quality
bone marrow	UBERON:0002371	54.90	gold quality
endometrium	UBERON:0001295	53.36	gold quality
left coronary artery	UBERON:0001626	53.21	gold quality
smooth muscle tissue	UBERON:0001135	53.13	gold quality
duodenum	UBERON:0002114	53.00	gold quality
prefrontal cortex	UBERON:0000451	52.82	gold quality
primary visual cortex	UBERON:0002436	52.60	gold quality
lung	UBERON:0002048	52.59	gold quality
right coronary artery	UBERON:0001625	52.33	gold quality
urinary bladder	UBERON:0001255	51.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.