LINC01424

Summary

LINC01424 (long intergenic non-protein coding RNA 1424, HGNC:40558) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40558
Approved symbol	LINC01424
Name	long intergenic non-protein coding RNA 1424
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236519
Ensembl biotype	lncRNA
Entrez	101928689
RNAcentral	URS000075B98B — lncRNA, 1374 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000417820, ENST00000692279, ENST00000701588

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417820 — 2 exons

Exon	Start	End
ENSE00001648916	44803747	44804717
ENSE00001654036	44802577	44802636

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 81.27.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1486 / max 20.0259, expressed in 582 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189496	1.1486	582

Top tissues by expression

248 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.27	silver quality
bone marrow cell	CL:0002092	76.87	gold quality
right testis	UBERON:0004534	75.48	gold quality
left testis	UBERON:0004533	75.04	gold quality
testis	UBERON:0000473	72.82	gold quality
sperm	CL:0000019	69.10	gold quality
sural nerve	UBERON:0015488	65.69	silver quality
cortical plate	UBERON:0005343	64.99	gold quality
right uterine tube	UBERON:0001302	63.13	gold quality
ganglionic eminence	UBERON:0004023	60.61	gold quality
mucosa of transverse colon	UBERON:0004991	60.08	gold quality
right lobe of thyroid gland	UBERON:0001119	58.59	gold quality
tibialis anterior	UBERON:0001385	58.58	silver quality
cerebellar hemisphere	UBERON:0002245	57.67	gold quality
cerebellar cortex	UBERON:0002129	57.63	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.58	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.32	gold quality
stromal cell of endometrium	CL:0002255	57.03	gold quality
cerebellum	UBERON:0002037	56.39	gold quality
left lobe of thyroid gland	UBERON:0001120	56.20	gold quality
thyroid gland	UBERON:0002046	56.12	gold quality
calcaneal tendon	UBERON:0003701	55.62	gold quality
lymph node	UBERON:0000029	55.47	gold quality
left ovary	UBERON:0002119	54.99	gold quality
pancreatic ductal cell	CL:0002079	54.79	silver quality
adult organism	UBERON:0007023	54.75	gold quality
granulocyte	CL:0000094	54.50	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
ileal mucosa	UBERON:0000331	54.33	silver quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.