LINC01428

Summary

LINC01428 (long intergenic non-protein coding RNA 1428, HGNC:50738) is a long non-coding RNA gene on chromosome 20p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50738
Approved symbol	LINC01428
Name	long intergenic non-protein coding RNA 1428
Location	20p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228888
Ensembl biotype	lncRNA
Entrez	101929265
RNAcentral	URS000075BF90 — lncRNA, 898 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000428954, ENST00000449581, ENST00000661779, ENST00000668728, ENST00000688958, ENST00000702434, ENST00000716638, ENST00000716639, ENST00000716640, ENST00000828086, ENST00000834213

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428954 — 2 exons

Exon	Start	End
ENSE00004251541	7252153	7256850
ENSE00004251544	7258098	7258353

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 53.89.

Top tissues by expression

175 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	53.89	gold quality
calcaneal tendon	UBERON:0003701	52.71	silver quality
heart left ventricle	UBERON:0002084	51.50	gold quality
sperm	CL:0000019	51.28	gold quality
muscle of leg	UBERON:0001383	51.28	gold quality
anterior cingulate cortex	UBERON:0009835	51.17	gold quality
cardiac ventricle	UBERON:0002082	51.01	gold quality
heart	UBERON:0000948	50.28	gold quality
gastrocnemius	UBERON:0001388	49.93	gold quality
liver	UBERON:0002107	49.62	gold quality
right atrium auricular region	UBERON:0006631	48.85	gold quality
gall bladder	UBERON:0002110	48.67	gold quality
cardiac atrium	UBERON:0002081	48.50	gold quality
islet of Langerhans	UBERON:0000006	48.27	gold quality
upper leg skin	UBERON:0004262	47.45	silver quality
cortex of kidney	UBERON:0001225	47.04	gold quality
monocyte	CL:0000576	46.63	silver quality
adult mammalian kidney	UBERON:0000082	46.40	gold quality
lymph node	UBERON:0000029	46.08	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	44.59	silver quality
kidney	UBERON:0002113	43.51	gold quality
pancreas	UBERON:0001264	43.44	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
skeletal muscle tissue	UBERON:0001134	42.32	gold quality
blood	UBERON:0000178	42.15	gold quality
anatomical system	UBERON:0000467	41.83	gold quality
material anatomical entity	UBERON:0000465	41.73	gold quality
multicellular organism	UBERON:0000468	41.71	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Whole genome sequencing identifies associations for nonsyndromic sagittal craniosynostosis with the intergenic region of BMP2 and noncoding RNA gene LINC01428. (PMID:38609424)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.