LINC01435

Summary

LINC01435 (long intergenic non-protein coding RNA 1435, HGNC:50753) is a long non-coding RNA gene on chromosome 10q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50753
Approved symbol	LINC01435
Name	long intergenic non-protein coding RNA 1435
Location	10q25.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-215N21.1, TCONS_00018040
Ensembl gene	ENSG00000229981
Ensembl biotype	lncRNA
Entrez	103695365
RNAcentral	URS00007E3821 — lncRNA, 732 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 33 — 33 lncRNA

ENST00000425050, ENST00000593666, ENST00000594427, ENST00000594566, ENST00000595603, ENST00000596000, ENST00000596263, ENST00000597234, ENST00000597243, ENST00000598903, ENST00000600953, ENST00000601212, ENST00000601410, ENST00000601466, ENST00000601505, ENST00000607995, ENST00000622852, ENST00000627225, ENST00000629275, ENST00000630847, ENST00000631100, ENST00000654674, ENST00000656439, ENST00000659061, ENST00000665974, ENST00000760057, ENST00000809134, ENST00000809135, ENST00000809136, ENST00000809137, ENST00000809138, ENST00000809139, ENST00000809140

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425050 — 5 exons

Exon	Start	End
ENSE00001683754	108043178	108043324
ENSE00001709964	108040361	108040498
ENSE00001724335	108069182	108069294
ENSE00001769925	108041049	108041194
ENSE00001774322	107871576	107871753

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 82.02.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.02	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.72	gold quality
monocyte	CL:0000576	66.15	gold quality
leukocyte	CL:0000738	65.97	gold quality
ventricular zone	UBERON:0003053	64.54	gold quality
cortical plate	UBERON:0005343	64.46	gold quality
ganglionic eminence	UBERON:0004023	62.78	gold quality
bone marrow	UBERON:0002371	61.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.85	gold quality
fundus of stomach	UBERON:0001160	58.32	gold quality
sural nerve	UBERON:0015488	57.65	silver quality
blood	UBERON:0000178	55.85	gold quality
body of pancreas	UBERON:0001150	55.49	gold quality
pancreas	UBERON:0001264	55.46	gold quality
liver	UBERON:0002107	55.42	gold quality
prefrontal cortex	UBERON:0000451	55.29	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.95	gold quality
kidney	UBERON:0002113	54.75	gold quality
muscle tissue	UBERON:0002385	54.69	gold quality
islet of Langerhans	UBERON:0000006	54.32	gold quality
cortex of kidney	UBERON:0001225	54.17	gold quality
superior frontal gyrus	UBERON:0002661	53.62	gold quality
right coronary artery	UBERON:0001625	53.56	gold quality
placenta	UBERON:0001987	53.38	gold quality
adult mammalian kidney	UBERON:0000082	52.78	gold quality
tibial nerve	UBERON:0001323	52.34	gold quality
myometrium	UBERON:0001296	51.52	gold quality
left coronary artery	UBERON:0001626	51.48	gold quality
metanephros cortex	UBERON:0010533	51.42	gold quality
lymph node	UBERON:0000029	51.32	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 3.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	3070.75
E-GEOD-131882	yes	2839.70
E-ANND-3	yes	6.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.