LINC01445

Summary

LINC01445 (long intergenic non-protein coding RNA 1445, HGNC:50771) is a long non-coding RNA gene on chromosome 7p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50771
Approved symbol	LINC01445
Name	long intergenic non-protein coding RNA 1445
Location	7p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231427
Ensembl biotype	lncRNA
Entrez	102723605
RNAcentral	URS000075EC17 — lncRNA, 1142 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000426205, ENST00000458615, ENST00000654826, ENST00000654951, ENST00000659445, ENST00000660245, ENST00000661025, ENST00000666100, ENST00000666668, ENST00000668540, ENST00000669187, ENST00000669611, ENST00000669718, ENST00000765948, ENST00000765949

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426205 — 3 exons

Exon	Start	End
ENSE00001651252	54347294	54347365
ENSE00004124311	54348898	54349853
ENSE00004124313	54330700	54330818

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 89.00.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3750 / max 54.2742, expressed in 70 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
78663	0.3750	70

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	89.00	gold quality
spinal cord	UBERON:0002240	88.99	gold quality
corpus callosum	UBERON:0002336	83.76	gold quality
substantia nigra	UBERON:0002038	80.37	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.73	gold quality
cerebellar vermis	UBERON:0004720	73.49	gold quality
Ammon’s horn	UBERON:0001954	72.65	gold quality
primary visual cortex	UBERON:0002436	68.18	gold quality
hypothalamus	UBERON:0001898	66.82	gold quality
prefrontal cortex	UBERON:0000451	65.48	gold quality
amygdala	UBERON:0001876	64.71	gold quality
temporal lobe	UBERON:0001871	64.65	gold quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
putamen	UBERON:0001874	63.58	gold quality
caudate nucleus	UBERON:0001873	62.54	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.16	gold quality
cerebral cortex	UBERON:0000956	61.34	gold quality
frontal cortex	UBERON:0001870	60.64	gold quality
thymus	UBERON:0002370	60.58	silver quality
brain	UBERON:0000955	60.55	gold quality
nucleus accumbens	UBERON:0001882	60.29	gold quality
bone marrow	UBERON:0002371	60.00	silver quality
ventricular zone	UBERON:0003053	59.15	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	58.11	gold quality
testis	UBERON:0000473	56.67	gold quality
anterior cingulate cortex	UBERON:0009835	56.66	gold quality
ganglionic eminence	UBERON:0004023	56.26	silver quality
left testis	UBERON:0004533	56.04	gold quality
right testis	UBERON:0004534	55.52	gold quality
superior frontal gyrus	UBERON:0002661	54.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.