LINC01449

Summary

LINC01449 (long intergenic non-protein coding RNA 1449, HGNC:50791) is a long non-coding RNA gene on chromosome 7p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50791
Approved symbol	LINC01449
Name	long intergenic non-protein coding RNA 1449
Location	7p14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224017
Ensembl biotype	lncRNA
Entrez	101928773
RNAcentral	URS000075EF3C — lncRNA, 1214 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000440213, ENST00000665804, ENST00000666072, ENST00000667448, ENST00000790468, ENST00000790469

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440213 — 6 exons

Exon	Start	End
ENSE00001601864	41133224	41133507
ENSE00001621638	41101604	41101859
ENSE00001685322	41107859	41107923
ENSE00001717430	41118967	41119283
ENSE00001746439	41130672	41130849
ENSE00001799274	41112444	41112563

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 75.20.

Top tissues by expression

190 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.20	gold quality
sural nerve	UBERON:0015488	68.96	silver quality
ascending aorta	UBERON:0001496	67.35	gold quality
thoracic aorta	UBERON:0001515	67.24	gold quality
buccal mucosa cell	CL:0002336	66.60	gold quality
ventricular zone	UBERON:0003053	65.38	gold quality
descending thoracic aorta	UBERON:0002345	64.01	gold quality
right coronary artery	UBERON:0001625	62.85	gold quality
left coronary artery	UBERON:0001626	61.41	gold quality
aorta	UBERON:0000947	60.80	gold quality
coronary artery	UBERON:0001621	60.28	gold quality
right adrenal gland cortex	UBERON:0035827	58.15	gold quality
popliteal artery	UBERON:0002250	56.01	gold quality
tibial artery	UBERON:0007610	56.01	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.76	silver quality
left adrenal gland cortex	UBERON:0035825	54.90	gold quality
right adrenal gland	UBERON:0001233	54.77	gold quality
adrenal cortex	UBERON:0001235	54.45	gold quality
calcaneal tendon	UBERON:0003701	54.27	gold quality
left adrenal gland	UBERON:0001234	53.10	gold quality
sperm	CL:0000019	52.81	gold quality
adrenal gland	UBERON:0002369	52.42	gold quality
skin of leg	UBERON:0001511	49.98	gold quality
monocyte	CL:0000576	49.75	silver quality
skin of abdomen	UBERON:0001416	49.52	gold quality
heart	UBERON:0000948	49.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	48.97	gold quality
gall bladder	UBERON:0002110	48.62	gold quality
prefrontal cortex	UBERON:0000451	48.56	gold quality
muscle of leg	UBERON:0001383	48.56	silver quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.61
E-HCAD-30	no	51.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.