LINC01451

Summary

LINC01451 (long intergenic non-protein coding RNA 1451, HGNC:48599) is a long non-coding RNA gene on chromosome 9q34.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48599
Approved symbol	LINC01451
Name	long intergenic non-protein coding RNA 1451
Location	9q34.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000279141
Ensembl biotype	lncRNA
Entrez	401561
RNAcentral	URS0000811A17 — lncRNA, 3402 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000626304, ENST00000628780, ENST00000798055, ENST00000798056, ENST00000798057, ENST00000798058, ENST00000798059, ENST00000798060, ENST00000798061, ENST00000798062, ENST00000798063

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000626304 — 4 exons

Exon	Start	End
ENSE00003760903	136615095	136615263
ENSE00003761601	136612024	136612170
ENSE00003766180	136612703	136612903
ENSE00003767954	136615361	136615637

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 86.66.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	86.66	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.65	silver quality
granulocyte	CL:0000094	75.95	gold quality
skin of abdomen	UBERON:0001416	74.32	gold quality
lower esophagus mucosa	UBERON:0035834	74.24	gold quality
bone marrow cell	CL:0002092	72.23	silver quality
zone of skin	UBERON:0000014	71.93	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.61	gold quality
skin of leg	UBERON:0001511	70.06	gold quality
esophagus mucosa	UBERON:0002469	69.00	gold quality
right lobe of liver	UBERON:0001114	67.09	gold quality
urinary bladder	UBERON:0001255	66.19	gold quality
liver	UBERON:0002107	65.89	gold quality
blood	UBERON:0000178	65.76	gold quality
prostate gland	UBERON:0002367	65.61	gold quality
small intestine Peyer’s patch	UBERON:0003454	65.56	gold quality
skeletal muscle tissue	UBERON:0001134	65.38	silver quality
small intestine	UBERON:0002108	65.11	gold quality
vagina	UBERON:0000996	64.55	gold quality
bone marrow	UBERON:0002371	63.80	gold quality
transverse colon	UBERON:0001157	61.58	gold quality
ventricular zone	UBERON:0003053	61.50	gold quality
mucosa of transverse colon	UBERON:0004991	61.44	gold quality
esophagus	UBERON:0001043	60.84	gold quality
tonsil	UBERON:0002372	60.33	gold quality
intestine	UBERON:0000160	59.67	gold quality
ganglionic eminence	UBERON:0004023	59.29	gold quality
rectum	UBERON:0001052	57.72	gold quality
colon	UBERON:0001155	57.37	gold quality
duodenum	UBERON:0002114	56.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.65

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01451 drives epithelial-mesenchymal transition and progression in bladder cancer cells via LIN28/TGF-beta/Smad pathway. (PMID:33516780)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.