LINC01480

Summary

LINC01480 (long intergenic non-protein coding RNA 1480, HGNC:51124) is a long non-coding RNA gene on chromosome 19q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51124
Approved symbol	LINC01480
Name	long intergenic non-protein coding RNA 1480
Location	19q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000270164
Ensembl biotype	lncRNA
Entrez	101927931
RNAcentral	URS000075A984 — lncRNA, 478 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 49 — 49 lncRNA

ENST00000483481, ENST00000487420, ENST00000494375, ENST00000597199, ENST00000599316, ENST00000599770, ENST00000685659, ENST00000688356, ENST00000702782, ENST00000716303, ENST00000788803, ENST00000788804, ENST00000788805, ENST00000788806, ENST00000788807, ENST00000788808, ENST00000788809, ENST00000788810, ENST00000788811, ENST00000788812, ENST00000788813, ENST00000788814, ENST00000788815, ENST00000788816, ENST00000788817, ENST00000788818, ENST00000788819, ENST00000788820, ENST00000788821, ENST00000788822, ENST00000788823, ENST00000788824, ENST00000788825, ENST00000788826, ENST00000788827, ENST00000788828, ENST00000788829, ENST00000788830, ENST00000788831, ENST00000788832, ENST00000788833, ENST00000788834, ENST00000788835, ENST00000788836, ENST00000788837, ENST00000788838, ENST00000788839, ENST00000788840, ENST00000788841

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000483481 — 3 exons

Exon	Start	End
ENSE00001817348	41535728	41535783
ENSE00004167591	41535183	41535601
ENSE00004167646	41536598	41536905

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 86.41.

FANTOM5 (CAGE): breadth broad, TPM avg 1.4356 / max 261.2598, expressed in 309 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
176039	1.0713	270
176036	0.3006	94
176037	0.0341	15
176038	0.0295	14

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lymph node	UBERON:0000029	86.41	gold quality
endometrium	UBERON:0001295	83.28	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.25	gold quality
spleen	UBERON:0002106	82.03	gold quality
bone marrow cell	CL:0002092	77.10	gold quality
vermiform appendix	UBERON:0001154	76.91	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	75.43	gold quality
tonsil	UBERON:0002372	74.44	gold quality
small intestine Peyer’s patch	UBERON:0003454	73.42	gold quality
substantia nigra	UBERON:0002038	72.69	gold quality
granulocyte	CL:0000094	72.67	gold quality
rectum	UBERON:0001052	72.67	gold quality
small intestine	UBERON:0002108	72.46	gold quality
right coronary artery	UBERON:0001625	71.23	gold quality
bone marrow	UBERON:0002371	71.05	gold quality
blood	UBERON:0000178	70.85	gold quality
right lung	UBERON:0002167	70.70	gold quality
muscle tissue	UBERON:0002385	69.94	gold quality
saliva-secreting gland	UBERON:0001044	69.82	gold quality
upper lobe of left lung	UBERON:0008952	69.66	gold quality
minor salivary gland	UBERON:0001830	69.50	gold quality
colonic epithelium	UBERON:0000397	69.47	silver quality
apex of heart	UBERON:0002098	69.18	gold quality
placenta	UBERON:0001987	68.81	gold quality
prostate gland	UBERON:0002367	68.70	gold quality
gall bladder	UBERON:0002110	68.32	gold quality
mucosa of transverse colon	UBERON:0004991	68.17	gold quality
omental fat pad	UBERON:0010414	68.03	gold quality
thoracic mammary gland	UBERON:0005200	67.21	gold quality
transverse colon	UBERON:0001157	66.59	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-10287	yes	48.26
E-ANND-3	yes	7.38

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Long non-coding RNA LINC01480 is activated by Foxo3a and promotes hydroquinone-induced TK6 cell apoptosis by inhibiting the PI3K/AKT pathway. (PMID:36934544)
• LINC01480 as a Prognostic Biomarker Associated With Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma. (PMID:37351956)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.