LINC01483

Summary

LINC01483 (long intergenic non-protein coding RNA 1483, HGNC:51130) is a long non-coding RNA gene on chromosome 17q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51130
Approved symbol	LINC01483
Name	long intergenic non-protein coding RNA 1483
Location	17q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227517
Ensembl biotype	lncRNA
Entrez	101928122
RNAcentral	URS000075AB2D — lncRNA, 712 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 72 — 72 lncRNA

ENST00000433856, ENST00000587241, ENST00000588185, ENST00000588501, ENST00000591334, ENST00000659331, ENST00000665875, ENST00000778376, ENST00000778377, ENST00000778378, ENST00000778379, ENST00000778380, ENST00000778381, ENST00000778382, ENST00000778383, ENST00000778384, ENST00000778385, ENST00000778386, ENST00000778387, ENST00000778388, ENST00000778389, ENST00000778390, ENST00000778391, ENST00000778392, ENST00000778393, ENST00000778394, ENST00000778395, ENST00000778396, ENST00000778397, ENST00000778398, ENST00000778399, ENST00000778400, ENST00000778401, ENST00000778402, ENST00000778403, ENST00000778404, ENST00000778405, ENST00000778406, ENST00000778407, ENST00000778408, ENST00000778409, ENST00000778410, ENST00000778411, ENST00000778412, ENST00000778413, ENST00000778414, ENST00000778415, ENST00000778416, ENST00000778417, ENST00000778418, ENST00000778419, ENST00000778420, ENST00000778421, ENST00000778422, ENST00000778423, ENST00000778424, ENST00000778425, ENST00000778426, ENST00000778427, ENST00000778428, ENST00000778429, ENST00000778430, ENST00000778431, ENST00000778432, ENST00000778433, ENST00000778434, ENST00000778435, ENST00000778436, ENST00000778437, ENST00000778438, ENST00000778439, ENST00000778440

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433856 — 3 exons

Exon	Start	End
ENSE00001702079	69625506	69628351
ENSE00001802669	69594785	69594940
ENSE00004147827	69624670	69624752

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 77.90.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0658 / max 12.6381, expressed in 18 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
162471	0.0308	8
162477	0.0288	9
162469	0.0049	3
162470	0.0014	1

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.90	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.08	gold quality
right adrenal gland cortex	UBERON:0035827	71.81	gold quality
muscle tissue	UBERON:0002385	70.34	gold quality
right adrenal gland	UBERON:0001233	70.19	gold quality
left adrenal gland	UBERON:0001234	70.01	gold quality
adrenal gland	UBERON:0002369	69.87	gold quality
left adrenal gland cortex	UBERON:0035825	69.59	gold quality
skeletal muscle tissue	UBERON:0001134	69.46	gold quality
placenta	UBERON:0001987	69.15	gold quality
ventricular zone	UBERON:0003053	68.36	gold quality
colonic epithelium	UBERON:0000397	67.79	silver quality
bone marrow cell	CL:0002092	67.76	silver quality
bone marrow	UBERON:0002371	67.11	gold quality
calcaneal tendon	UBERON:0003701	65.28	gold quality
lymph node	UBERON:0000029	64.16	gold quality
right lobe of thyroid gland	UBERON:0001119	59.98	gold quality
left lobe of thyroid gland	UBERON:0001120	58.76	gold quality
thyroid gland	UBERON:0002046	58.73	gold quality
muscle of leg	UBERON:0001383	57.39	gold quality
gastrocnemius	UBERON:0001388	57.20	gold quality
right testis	UBERON:0004534	56.56	gold quality
monocyte	CL:0000576	56.14	gold quality
islet of Langerhans	UBERON:0000006	56.05	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.65	gold quality
blood	UBERON:0000178	55.44	gold quality
tonsil	UBERON:0002372	55.14	gold quality
testis	UBERON:0000473	54.82	gold quality
prefrontal cortex	UBERON:0000451	54.26	gold quality
left testis	UBERON:0004533	53.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.07

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• three novel MD loci were identified (at P < 5 x 10(- 8)): one for percent dense volume (HABP2) and two for the absolute dense volume (INHBB, LINC01483). INHBB is an established locus for ER-negative breast cancer, and HABP2 and LINC01483 represent putative new breast cancer susceptibility loci (PMID:29665850)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.