LINC01497

Summary

LINC01497 (long intergenic non-protein coding RNA 1497, HGNC:51163) is a long non-coding RNA gene on chromosome 17q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51163
Approved symbol	LINC01497
Name	long intergenic non-protein coding RNA 1497
Location	17q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237560
Ensembl biotype	lncRNA
Entrez	102723487
RNAcentral	URS000075CD1C — lncRNA, 726 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 43 — 43 lncRNA

ENST00000420427, ENST00000455460, ENST00000649355, ENST00000654068, ENST00000654711, ENST00000685530, ENST00000692412, ENST00000701053, ENST00000702106, ENST00000734471, ENST00000734472, ENST00000734473, ENST00000734474, ENST00000734475, ENST00000734476, ENST00000734477, ENST00000734478, ENST00000734479, ENST00000734480, ENST00000734481, ENST00000734482, ENST00000734483, ENST00000734484, ENST00000734485, ENST00000734486, ENST00000734487, ENST00000734488, ENST00000734489, ENST00000734490, ENST00000734491, ENST00000734492, ENST00000734493, ENST00000734494, ENST00000734495, ENST00000734496, ENST00000734497, ENST00000734498, ENST00000734499, ENST00000734500, ENST00000734501, ENST00000734502, ENST00000734503, ENST00000734504

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420427 — 5 exons

Exon	Start	End
ENSE00001600996	69964382	69964552
ENSE00001691132	69983385	69983545
ENSE00001801589	69982329	69982462
ENSE00001804988	69981244	69981373
ENSE00004066607	69961544	69961837

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 94.64.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2209 / max 83.1536, expressed in 49 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
162480	0.1512	44
162481	0.0454	13
162482	0.0164	6
162483	0.0079	5

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	94.64	gold quality
bone marrow	UBERON:0002371	86.92	silver quality
thymus	UBERON:0002370	82.84	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.33	silver quality
skeletal muscle tissue	UBERON:0001134	67.84	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.91	gold quality
islet of Langerhans	UBERON:0000006	63.62	gold quality
hypothalamus	UBERON:0001898	62.25	gold quality
muscle of leg	UBERON:0001383	62.09	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.82	gold quality
gastrocnemius	UBERON:0001388	61.67	gold quality
right adrenal gland cortex	UBERON:0035827	61.32	gold quality
substantia nigra	UBERON:0002038	61.30	gold quality
ovary	UBERON:0000992	60.81	gold quality
left ovary	UBERON:0002119	60.53	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.37	gold quality
thoracic mammary gland	UBERON:0005200	59.18	gold quality
left adrenal gland	UBERON:0001234	59.16	gold quality
adrenal gland	UBERON:0002369	58.69	gold quality
left adrenal gland cortex	UBERON:0035825	58.66	gold quality
pancreas	UBERON:0001264	57.52	gold quality
right adrenal gland	UBERON:0001233	56.89	gold quality
right ovary	UBERON:0002118	56.70	gold quality
endometrium	UBERON:0001295	56.54	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	56.43	gold quality
prefrontal cortex	UBERON:0000451	56.08	gold quality
tibial nerve	UBERON:0001323	55.99	gold quality
lower esophagus muscularis layer	UBERON:0035833	55.96	gold quality
lower esophagus	UBERON:0013473	55.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.