LINC01508

Summary

LINC01508 (long intergenic non-protein coding RNA 1508, HGNC:51190) is a long non-coding RNA gene on chromosome 9q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51190
Approved symbol	LINC01508
Name	long intergenic non-protein coding RNA 1508
Location	9q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231107
Ensembl biotype	lncRNA
Entrez	101927873
RNAcentral	URS000075A2E1 — lncRNA, 1030 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000425666, ENST00000436671, ENST00000659218, ENST00000785640, ENST00000785641

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425666 — 3 exons

Exon	Start	End
ENSE00001605021	90383520	90383721
ENSE00004161620	90300885	90301653
ENSE00004161622	90433431	90433684

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 82.08.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8424 / max 80.5202, expressed in 266 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
101336	0.6513	245
101335	0.1911	94

Top tissues by expression

99 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.08	gold quality
left lobe of thyroid gland	UBERON:0001120	67.90	gold quality
thyroid gland	UBERON:0002046	67.36	gold quality
right lobe of thyroid gland	UBERON:0001119	65.90	gold quality
endocervix	UBERON:0000458	63.20	gold quality
adult mammalian kidney	UBERON:0000082	62.57	gold quality
kidney	UBERON:0002113	61.51	gold quality
cortex of kidney	UBERON:0001225	60.26	gold quality
ganglionic eminence	UBERON:0004023	59.82	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.81	gold quality
stromal cell of endometrium	CL:0002255	59.74	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.70	gold quality
cerebellum	UBERON:0002037	57.69	gold quality
cerebellar cortex	UBERON:0002129	57.56	gold quality
cerebellar hemisphere	UBERON:0002245	57.44	gold quality
islet of Langerhans	UBERON:0000006	56.88	gold quality
urinary bladder	UBERON:0001255	56.02	gold quality
metanephros cortex	UBERON:0010533	55.25	gold quality
prefrontal cortex	UBERON:0000451	54.62	gold quality
placenta	UBERON:0001987	54.16	gold quality
liver	UBERON:0002107	52.36	silver quality
fallopian tube	UBERON:0003889	51.80	gold quality
lymph node	UBERON:0000029	51.53	silver quality
upper lobe of left lung	UBERON:0008952	51.37	gold quality
adrenal tissue	UBERON:0018303	51.27	gold quality
lung	UBERON:0002048	51.03	gold quality
myometrium	UBERON:0001296	50.56	gold quality
blood	UBERON:0000178	50.03	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.66	gold quality
frontal cortex	UBERON:0001870	49.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Downregulation of LINC01508 contributes to cisplatin resistance in ovarian cancer via the regulation of the Hippo-YAP pathway. (PMID:34132072)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.