LINC01538

Summary

LINC01538 (long intergenic non-protein coding RNA 1538, HGNC:51306) is a long non-coding RNA gene on chromosome 18q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51306
Approved symbol	LINC01538
Name	long intergenic non-protein coding RNA 1538
Location	18q22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00026184, RP11-909B2.1
Ensembl gene	ENSG00000266952
Ensembl biotype	lncRNA
Entrez	400654
RNAcentral	URS000075C66D — lncRNA, 2418 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000588074, ENST00000649058

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000588074 — 3 exons

Exon	Start	End
ENSE00002760671	64258218	64258519
ENSE00002807505	64213082	64215046
ENSE00002871882	64259915	64260055

Expression profiles

Bgee: expression breadth broad, 50 present calls, max score 83.07.

Top tissues by expression

169 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.07	gold quality
sural nerve	UBERON:0015488	66.32	silver quality
monocyte	CL:0000576	51.67	silver quality
lower lobe of lung	UBERON:0008949	47.89	silver quality
islet of Langerhans	UBERON:0000006	46.60	gold quality
gall bladder	UBERON:0002110	46.24	silver quality
gastrocnemius	UBERON:0001388	45.40	silver quality
pancreas	UBERON:0001264	44.79	silver quality
cortex of kidney	UBERON:0001225	44.72	silver quality
adrenal tissue	UBERON:0018303	44.27	silver quality
adult mammalian kidney	UBERON:0000082	44.26	gold quality
hindlimb stylopod muscle	UBERON:0004252	44.04	silver quality
putamen	UBERON:0001874	43.81	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
lymph node	UBERON:0000029	43.19	gold quality
caudate nucleus	UBERON:0001873	43.07	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
blood	UBERON:0000178	42.29	gold quality
kidney	UBERON:0002113	42.11	silver quality
nucleus accumbens	UBERON:0001882	42.02	gold quality
amygdala	UBERON:0001876	41.89	silver quality
right atrium auricular region	UBERON:0006631	41.77	silver quality
oviduct epithelium	UBERON:0004804	41.54	gold quality
vagina	UBERON:0000996	41.48	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
descending thoracic aorta	UBERON:0002345	41.31	silver quality
hypothalamus	UBERON:0001898	41.27	gold quality
bone marrow	UBERON:0002371	41.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.