LINC01566

Summary

LINC01566 (long intergenic non-protein coding RNA 1566, HGNC:27555) is a long non-coding RNA gene on chromosome 16p11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27555
Approved symbol	LINC01566
Name	long intergenic non-protein coding RNA 1566
Location	16p11.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259841
Ensembl biotype	lncRNA
Entrez	283914
RNAcentral	URS000075B08B — lncRNA, 2815 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000561756, ENST00000569242, ENST00000726698, ENST00000726699, ENST00000726700, ENST00000726701, ENST00000726702, ENST00000726703, ENST00000726704, ENST00000726705, ENST00000726706, ENST00000726707, ENST00000726708

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561756 — 5 exons

Exon	Start	End
ENSE00002582733	35363412	35363528
ENSE00002589780	35379969	35380087
ENSE00002607026	35376506	35376649
ENSE00004051504	35378572	35378813
ENSE00004051519	35382424	35382854

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 72.32.

Top tissues by expression

156 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	72.32	silver quality
gingival epithelium	UBERON:0001949	65.88	gold quality
buccal mucosa cell	CL:0002336	65.22	silver quality
gingiva	UBERON:0001828	61.74	gold quality
tibial nerve	UBERON:0001323	59.92	gold quality
nasal cavity epithelium	UBERON:0005384	58.92	gold quality
islet of Langerhans	UBERON:0000006	58.33	gold quality
secondary oocyte	CL:0000655	58.28	gold quality
oocyte	CL:0000023	57.46	gold quality
monocyte	CL:0000576	57.40	gold quality
cartilage tissue	UBERON:0002418	57.04	gold quality
tonsil	UBERON:0002372	56.94	gold quality
pericardium	UBERON:0002407	56.90	gold quality
skin of abdomen	UBERON:0001416	56.44	gold quality
skin of hip	UBERON:0001554	56.13	gold quality
parotid gland	UBERON:0001831	55.98	gold quality
cerebellar vermis	UBERON:0004720	55.09	gold quality
corpus epididymis	UBERON:0004359	52.44	gold quality
mammary duct	UBERON:0001765	52.40	gold quality
pigmented layer of retina	UBERON:0001782	52.40	gold quality
vastus lateralis	UBERON:0001379	52.19	gold quality
cauda epididymis	UBERON:0004360	52.04	gold quality
quadriceps femoris	UBERON:0001377	51.92	gold quality
decidua	UBERON:0002450	51.91	gold quality
caput epididymis	UBERON:0004358	51.91	gold quality
medial globus pallidus	UBERON:0002477	51.59	gold quality
zone of skin	UBERON:0000014	51.42	gold quality
cerebellum	UBERON:0002037	51.30	gold quality
pancreas	UBERON:0001264	51.04	gold quality
trabecular bone tissue	UBERON:0002483	50.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.94

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• FOSL1-mediated LINC01566 negatively regulates CD4[+] T-cell activation in myasthenia gravis. (PMID:39113081)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.