LINC01567

Summary

LINC01567 (long intergenic non-protein coding RNA 1567, HGNC:51367) is a long non-coding RNA gene on chromosome 16p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51367
Approved symbol	LINC01567
Name	long intergenic non-protein coding RNA 1567
Location	16p12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	LOCCS
Ensembl gene	ENSG00000224310
Ensembl biotype	lncRNA
Entrez	400511
RNAcentral	URS00005467C8 — lncRNA, 2907 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000414816

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414816 — 3 exons

Exon	Start	End
ENSE00001695724	24670927	24671062
ENSE00001703290	24661422	24664004
ENSE00001733309	24664838	24665025

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 72.53.

Top tissues by expression

56 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.53	silver quality
liver	UBERON:0002107	69.77	gold quality
uterine cervix	UBERON:0000002	68.67	silver quality
myometrium	UBERON:0001296	63.31	silver quality
colonic epithelium	UBERON:0000397	60.99	silver quality
ganglionic eminence	UBERON:0004023	57.53	silver quality
skeletal muscle tissue	UBERON:0001134	55.87	silver quality
cortex of kidney	UBERON:0001225	52.80	silver quality
kidney	UBERON:0002113	52.22	silver quality
primary visual cortex	UBERON:0002436	52.04	gold quality
superior frontal gyrus	UBERON:0002661	50.24	gold quality
corpus callosum	UBERON:0002336	49.90	silver quality
cerebellum	UBERON:0002037	49.02	gold quality
islet of Langerhans	UBERON:0000006	48.85	gold quality
cerebellar cortex	UBERON:0002129	48.79	gold quality
cerebellar hemisphere	UBERON:0002245	48.40	silver quality
adult mammalian kidney	UBERON:0000082	48.08	silver quality
prefrontal cortex	UBERON:0000451	47.64	gold quality
right hemisphere of cerebellum	UBERON:0014890	46.63	silver quality
pituitary gland	UBERON:0000007	45.73	gold quality
hindlimb stylopod muscle	UBERON:0004252	45.44	silver quality
adrenal tissue	UBERON:0018303	45.19	silver quality
ovary	UBERON:0000992	44.57	silver quality
colon	UBERON:0001155	43.82	silver quality
brain	UBERON:0000955	43.80	silver quality
frontal cortex	UBERON:0001870	42.98	silver quality
skin of leg	UBERON:0001511	42.58	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.55	silver quality
tibial artery	UBERON:0007610	42.50	silver quality
adenohypophysis	UBERON:0002196	42.36	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.77

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Results show that LINC01567 is up-regulated in colon neoplasm cancer stem cells. Its knockdown reduced cell proliferation, invasion, migration, and generation of tumor xenografts. Also, a reciprocal repression between LOCCS and miR-93 is found. (PMID:29110645)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.