LINC01572

Summary

LINC01572 (long intergenic non-protein coding RNA 1572, HGNC:51385) is a long non-coding RNA gene on chromosome 16q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51385
Approved symbol	LINC01572
Name	long intergenic non-protein coding RNA 1572
Location	16q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261008
Ensembl biotype	lncRNA
Entrez	101927957
RNAcentral	URS0000D77FFD — lncRNA, 4088 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 112 — 112 lncRNA

ENST00000561611, ENST00000563770, ENST00000563823, ENST00000570035, ENST00000570152, ENST00000624829, ENST00000653104, ENST00000655530, ENST00000656218, ENST00000657725, ENST00000659470, ENST00000661899, ENST00000662171, ENST00000664155, ENST00000664779, ENST00000666555, ENST00000668081, ENST00000669279, ENST00000691892, ENST00000701925, ENST00000766023, ENST00000766024, ENST00000766025, ENST00000766026, ENST00000766027, ENST00000766028, ENST00000766029, ENST00000766030, ENST00000766031, ENST00000766032, ENST00000766033, ENST00000766034, ENST00000766035, ENST00000766036, ENST00000766037, ENST00000766038, ENST00000766039, ENST00000766040, ENST00000766041, ENST00000766042, ENST00000766043, ENST00000766044, ENST00000766045, ENST00000766046, ENST00000766047, ENST00000766048, ENST00000766049, ENST00000766050, ENST00000766051, ENST00000766052, ENST00000766053, ENST00000766054, ENST00000766055, ENST00000766056, ENST00000766057, ENST00000766058, ENST00000766059, ENST00000766060, ENST00000766061, ENST00000766062, ENST00000766063, ENST00000766064, ENST00000766065, ENST00000766066, ENST00000766067, ENST00000766068, ENST00000766069, ENST00000766070, ENST00000766071, ENST00000766072, ENST00000766073, ENST00000766074, ENST00000766075, ENST00000766076, ENST00000766077, ENST00000766078, ENST00000766079, ENST00000766080, ENST00000766081, ENST00000766082, ENST00000766083, ENST00000766084, ENST00000766085, ENST00000766086, ENST00000766087, ENST00000766088, ENST00000766089, ENST00000766090, ENST00000766091, ENST00000766092, ENST00000766093, ENST00000766094, ENST00000766095, ENST00000766096, ENST00000766097, ENST00000766098, ENST00000766099, ENST00000766100, ENST00000766101, ENST00000766102, ENST00000766103, ENST00000766104, ENST00000766105, ENST00000766106, ENST00000766107, ENST00000766108, ENST00000766109, ENST00000766110, ENST00000766111, ENST00000766112, ENST00000766113, ENST00000766114

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561611 — 3 exons

Exon	Start	End
ENSE00002587715	72479683	72479790
ENSE00002594094	72664892	72665004
ENSE00002606893	72425485	72427457

Expression profiles

Bgee: expression breadth ubiquitous, 135 present calls, max score 85.93.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.6933 / max 178.9283, expressed in 1291 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
158070	5.6049	1263
158067	0.0885	21

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.93	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.95	gold quality
bone marrow cell	CL:0002092	80.43	gold quality
sural nerve	UBERON:0015488	78.79	gold quality
bone marrow	UBERON:0002371	77.27	gold quality
corpus callosum	UBERON:0002336	74.83	gold quality
colonic epithelium	UBERON:0000397	74.27	gold quality
ventricular zone	UBERON:0003053	73.95	gold quality
cortical plate	UBERON:0005343	71.12	gold quality
ganglionic eminence	UBERON:0004023	69.63	gold quality
tonsil	UBERON:0002372	69.04	gold quality
testis	UBERON:0000473	68.46	gold quality
left testis	UBERON:0004533	67.09	gold quality
esophagus mucosa	UBERON:0002469	66.83	gold quality
adrenal tissue	UBERON:0018303	66.82	gold quality
right testis	UBERON:0004534	66.47	gold quality
endometrium	UBERON:0001295	65.14	gold quality
primary visual cortex	UBERON:0002436	64.82	gold quality
prefrontal cortex	UBERON:0000451	64.70	gold quality
skeletal muscle tissue	UBERON:0001134	64.19	gold quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
monocyte	CL:0000576	63.74	gold quality
placenta	UBERON:0001987	63.58	gold quality
leukocyte	CL:0000738	63.19	gold quality
lymph node	UBERON:0000029	63.13	gold quality
spinal cord	UBERON:0002240	63.06	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.06	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
lower esophagus mucosa	UBERON:0035834	62.70	gold quality
substantia nigra	UBERON:0002038	62.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	5.51

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank. (PMID:32246137)
• LINC01572 is a Novel Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma. (PMID:37919058)
• LINC01572 promotes triple-negative breast cancer progression through EIF4A3-mediated beta-catenin mRNA nuclear exportation. (PMID:38317508)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.