LINC01574

Summary

LINC01574 (long intergenic non-protein coding RNA 1574, HGNC:51388) is a long non-coding RNA gene on chromosome 5q35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51388
Approved symbol	LINC01574
Name	long intergenic non-protein coding RNA 1574
Location	5q35.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	HI-LNC12, TCONS_00009551
Ensembl gene	ENSG00000248859
Ensembl biotype	lncRNA
Entrez	102577424
RNAcentral	URS000075D983 — lncRNA, 610 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000512115, ENST00000788262, ENST00000788263, ENST00000788264, ENST00000788265, ENST00000788266

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512115 — 2 exons

Exon	Start	End
ENSE00004166662	176743550	176743881
ENSE00004166675	176743205	176743442

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 74.62.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primary visual cortex	UBERON:0002436	74.62	gold quality
hypothalamus	UBERON:0001898	72.22	gold quality
superior frontal gyrus	UBERON:0002661	71.91	gold quality
anterior cingulate cortex	UBERON:0009835	71.29	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	70.99	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.49	gold quality
prefrontal cortex	UBERON:0000451	70.14	gold quality
cerebral cortex	UBERON:0000956	69.60	gold quality
frontal cortex	UBERON:0001870	69.44	gold quality
substantia nigra	UBERON:0002038	68.90	gold quality
temporal lobe	UBERON:0001871	68.55	gold quality
amygdala	UBERON:0001876	68.42	gold quality
right frontal lobe	UBERON:0002810	68.34	gold quality
brain	UBERON:0000955	67.97	gold quality
pituitary gland	UBERON:0000007	67.75	gold quality
cerebellum	UBERON:0002037	67.17	gold quality
cerebellar cortex	UBERON:0002129	67.04	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.03	gold quality
cerebellar hemisphere	UBERON:0002245	66.84	gold quality
ganglionic eminence	UBERON:0004023	66.25	gold quality
Ammon’s horn	UBERON:0001954	65.94	gold quality
nucleus accumbens	UBERON:0001882	65.47	gold quality
adenohypophysis	UBERON:0002196	65.31	gold quality
cortical plate	UBERON:0005343	64.27	gold quality
right adrenal gland cortex	UBERON:0035827	64.06	gold quality
putamen	UBERON:0001874	63.87	gold quality
caudate nucleus	UBERON:0001873	62.21	gold quality
islet of Langerhans	UBERON:0000006	60.35	gold quality
right adrenal gland	UBERON:0001233	60.20	gold quality
multicellular organism	UBERON:0000468	59.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• A Novel Identified Long Intergenic Noncoding RNA, LINC01574, Contributes to Breast Cancer Deterioration via the Regulation of miR-6745/TTYH3 Axis. (PMID:35935583)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.