LINC01586

Summary

LINC01586 (long intergenic non-protein coding RNA 1586, HGNC:51434) is a long non-coding RNA gene on chromosome 15q26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51434
Approved symbol	LINC01586
Name	long intergenic non-protein coding RNA 1586
Location	15q26.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00023252
Ensembl gene	ENSG00000249487
Ensembl biotype	lncRNA
Entrez	101929743
RNAcentral	URS000055732C — lncRNA, 1835 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000506090, ENST00000558835, ENST00000560368, ENST00000660022, ENST00000660890, ENST00000812004, ENST00000812005, ENST00000812006, ENST00000812007, ENST00000812008, ENST00000812009, ENST00000812010, ENST00000812011, ENST00000812012, ENST00000812013, ENST00000812014, ENST00000812015, ENST00000812016, ENST00000812017, ENST00000812018, ENST00000812019, ENST00000812020, ENST00000812021, ENST00000812022, ENST00000812023

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506090 — 3 exons

Exon	Start	End
ENSE00002073797	88603397	88603482
ENSE00004210564	88585565	88587062
ENSE00004210575	88604347	88604728

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 87.54.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	87.54	gold quality
pituitary gland	UBERON:0000007	79.86	gold quality
adenohypophysis	UBERON:0002196	76.72	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.93	silver quality
right lobe of thyroid gland	UBERON:0001119	73.92	gold quality
thyroid gland	UBERON:0002046	71.41	gold quality
colonic epithelium	UBERON:0000397	70.70	silver quality
ganglionic eminence	UBERON:0004023	70.65	gold quality
left lobe of thyroid gland	UBERON:0001120	69.88	gold quality
islet of Langerhans	UBERON:0000006	68.70	gold quality
prefrontal cortex	UBERON:0000451	64.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.98	silver quality
hypothalamus	UBERON:0001898	63.77	gold quality
frontal cortex	UBERON:0001870	63.01	gold quality
anterior cingulate cortex	UBERON:0009835	62.61	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.19	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.14	gold quality
cerebral cortex	UBERON:0000956	61.82	gold quality
omental fat pad	UBERON:0010414	61.02	gold quality
right frontal lobe	UBERON:0002810	60.77	gold quality
superior frontal gyrus	UBERON:0002661	60.49	gold quality
brain	UBERON:0000955	60.10	gold quality
temporal lobe	UBERON:0001871	59.96	gold quality
amygdala	UBERON:0001876	59.93	gold quality
ventricular zone	UBERON:0003053	58.79	silver quality
pancreas	UBERON:0001264	58.53	gold quality
Ammon’s horn	UBERON:0001954	58.04	gold quality
monocyte	CL:0000576	57.98	gold quality
adipose tissue	UBERON:0001013	57.37	gold quality
cerebellar hemisphere	UBERON:0002245	56.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.