LINC01587

Summary

LINC01587 (long intergenic non-protein coding RNA 1587, HGNC:13716) is a long non-coding RNA gene on chromosome 4p16.2.

This gene is expressed in neuroblastoma; however, the function of this gene is not yet determined.

Source: NCBI Gene 10141 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:13716
Approved symbol	LINC01587
Name	long intergenic non-protein coding RNA 1587
Location	4p16.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	aC1
Ensembl gene	ENSG00000082929
Ensembl biotype	lncRNA
Entrez	10141
RNAcentral	URS00007E356C — lncRNA, 909 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000504943, ENST00000505296, ENST00000515342, ENST00000623565, ENST00000818285, ENST00000818286, ENST00000818287

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504943 — 2 exons

Exon	Start	End
ENSE00002064894	5527388	5527801
ENSE00004222154	5527054	5527261

Expression profiles

Bgee: expression breadth ubiquitous, 138 present calls, max score 69.09.

Top tissues by expression

269 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	69.09	gold quality
sural nerve	UBERON:0015488	68.79	gold quality
gall bladder	UBERON:0002110	67.82	gold quality
ventricular zone	UBERON:0003053	65.45	gold quality
mucosa of stomach	UBERON:0001199	64.83	gold quality
right lobe of liver	UBERON:0001114	59.77	gold quality
calcaneal tendon	UBERON:0003701	58.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.17	gold quality
fallopian tube	UBERON:0003889	55.63	gold quality
adrenal tissue	UBERON:0018303	55.63	gold quality
stromal cell of endometrium	CL:0002255	55.45	gold quality
islet of Langerhans	UBERON:0000006	55.17	gold quality
corpus epididymis	UBERON:0004359	54.58	silver quality
monocyte	CL:0000576	54.33	gold quality
right uterine tube	UBERON:0001302	54.27	gold quality
mononuclear cell	CL:0000842	54.15	silver quality
esophagus mucosa	UBERON:0002469	53.96	gold quality
endometrium epithelium	UBERON:0004811	53.85	gold quality
cortex of kidney	UBERON:0001225	53.05	gold quality
minor salivary gland	UBERON:0001830	53.04	gold quality
lower esophagus mucosa	UBERON:0035834	52.61	gold quality
pancreas	UBERON:0001264	52.42	gold quality
smooth muscle tissue	UBERON:0001135	52.12	gold quality
esophagus	UBERON:0001043	51.90	gold quality
tibialis anterior	UBERON:0001385	51.54	silver quality
tonsil	UBERON:0002372	51.47	gold quality
saliva-secreting gland	UBERON:0001044	51.44	gold quality
mouth mucosa	UBERON:0003729	51.34	gold quality
muscle of leg	UBERON:0001383	51.20	gold quality
vermiform appendix	UBERON:0001154	51.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• In a consanguineous pedigree diagnosed with EvC and borderline intelligence, a 520-kb homozygous deletion comprising EVC, EVC2, C4orf6, and STK32B, caused by recombination between LINE-1 elements, was detected (PMID:18454448)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.