LINC01588

Summary

LINC01588 (long intergenic non-protein coding RNA 1588, HGNC:27503) is a long non-coding RNA gene on chromosome 14q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27503
Approved symbol	LINC01588
Name	long intergenic non-protein coding RNA 1588
Location	14q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000214900
Ensembl biotype	lncRNA
Entrez	283551
RNAcentral	URS00007E449F — lncRNA, 4835 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 134 — 134 lncRNA

ENST00000399206, ENST00000528300, ENST00000529902, ENST00000530176, ENST00000533506, ENST00000553463, ENST00000553914, ENST00000554129, ENST00000556019, ENST00000556130, ENST00000556434, ENST00000556913, ENST00000557142, ENST00000603228, ENST00000603474, ENST00000623502, ENST00000635379, ENST00000655269, ENST00000658223, ENST00000685750, ENST00000686177, ENST00000690038, ENST00000700829, ENST00000701026, ENST00000701065, ENST00000701392, ENST00000701890, ENST00000701948, ENST00000769199, ENST00000769200, ENST00000769201, ENST00000769202, ENST00000769203, ENST00000769204, ENST00000769205, ENST00000769206, ENST00000769207, ENST00000769208, ENST00000769209, ENST00000769210, ENST00000769211, ENST00000769212, ENST00000769213, ENST00000769214, ENST00000769215, ENST00000769216, ENST00000769217, ENST00000769218, ENST00000769219, ENST00000769220, ENST00000769221, ENST00000769222, ENST00000769223, ENST00000769224, ENST00000769225, ENST00000769226, ENST00000769227, ENST00000769228, ENST00000769229, ENST00000769230, ENST00000769231, ENST00000769232, ENST00000769233, ENST00000769234, ENST00000769235, ENST00000769236, ENST00000769237, ENST00000769238, ENST00000769239, ENST00000769240, ENST00000769241, ENST00000769242, ENST00000769243, ENST00000769244, ENST00000769245, ENST00000769246, ENST00000769247, ENST00000769248, ENST00000769249, ENST00000769250, ENST00000769251, ENST00000769252, ENST00000769253, ENST00000769254, ENST00000769255, ENST00000769256, ENST00000769257, ENST00000769258, ENST00000769259, ENST00000769260, ENST00000769261, ENST00000769262, ENST00000769263, ENST00000769264, ENST00000769265, ENST00000769266, ENST00000769267, ENST00000769268, ENST00000769269, ENST00000769270, ENST00000769271, ENST00000769272, ENST00000769273, ENST00000769274, ENST00000769275, ENST00000769276, ENST00000769277, ENST00000769278, ENST00000769279, ENST00000769280, ENST00000769281, ENST00000769282, ENST00000769283, ENST00000769284, ENST00000769285, ENST00000769286, ENST00000769287, ENST00000769288, ENST00000769289, ENST00000769290, ENST00000769291, ENST00000769292, ENST00000769293, ENST00000769294, ENST00000769295, ENST00000769296, ENST00000769297, ENST00000769298, ENST00000769299, ENST00000769300, ENST00000769301, ENST00000769302, ENST00000769303, ENST00000769304

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000399206 — 4 exons

Exon	Start	End
ENSE00001536941	49981712	49982304
ENSE00003517573	50005594	50007520
ENSE00003535993	49992256	49992325
ENSE00003630976	49992778	49992873

Expression profiles

Bgee: expression breadth ubiquitous, 166 present calls, max score 86.37.

FANTOM5 (CAGE): breadth broad, TPM avg 2.4167 / max 113.4441, expressed in 569 samples.

FANTOM5 promoters (12 alternative TSS)

Promoter ID	TPM avg	Samples expressed
143113	0.5418	110
143099	0.5322	134
143114	0.4608	93
143098	0.1860	105
143127	0.1789	63
143101	0.1756	64
143103	0.1746	109
143110	0.1432	40
143100	0.1049	48
143111	0.0390	17

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	86.37	gold quality
right uterine tube	UBERON:0001302	84.55	gold quality
mucosa of transverse colon	UBERON:0004991	84.29	gold quality
granulocyte	CL:0000094	83.60	gold quality
rectum	UBERON:0001052	80.58	gold quality
lymph node	UBERON:0000029	80.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.40	gold quality
spleen	UBERON:0002106	79.36	gold quality
vermiform appendix	UBERON:0001154	78.64	gold quality
blood	UBERON:0000178	77.43	gold quality
bone marrow cell	CL:0002092	77.08	gold quality
right adrenal gland	UBERON:0001233	77.00	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.78	gold quality
adrenal gland	UBERON:0002369	75.55	gold quality
right lobe of liver	UBERON:0001114	75.26	gold quality
small intestine Peyer’s patch	UBERON:0003454	75.10	gold quality
right adrenal gland cortex	UBERON:0035827	75.10	gold quality
esophagus mucosa	UBERON:0002469	75.03	gold quality
left adrenal gland cortex	UBERON:0035825	74.83	gold quality
left adrenal gland	UBERON:0001234	74.60	gold quality
caecum	UBERON:0001153	74.42	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.35	gold quality
adrenal cortex	UBERON:0001235	74.28	gold quality
lower esophagus mucosa	UBERON:0035834	74.18	gold quality
transverse colon	UBERON:0001157	73.97	gold quality
leukocyte	CL:0000738	73.91	gold quality
monocyte	CL:0000576	73.17	gold quality
small intestine	UBERON:0002108	73.13	gold quality
colonic epithelium	UBERON:0000397	72.70	gold quality
tonsil	UBERON:0002372	71.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.