LINC01591

Summary

LINC01591 (long intergenic non-protein coding RNA 1591, HGNC:27819) is a long non-coding RNA gene on chromosome 8q24.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27819
Approved symbol	LINC01591
Name	long intergenic non-protein coding RNA 1591
Location	8q24.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254083
Ensembl biotype	lncRNA
Entrez	286094
RNAcentral	URS000075D53B — lncRNA, 1260 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000520101, ENST00000522279, ENST00000524070, ENST00000657881, ENST00000660529

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000520101 — 4 exons

Exon	Start	End
ENSE00002091317	135234236	135234514
ENSE00002112899	135296497	135296555
ENSE00002113327	135291176	135291352
ENSE00002124547	135293758	135293870

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 65.98.

Top tissues by expression

54 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	65.98	gold quality
skeletal muscle tissue	UBERON:0001134	59.57	gold quality
right lobe of liver	UBERON:0001114	53.48	gold quality
muscle of leg	UBERON:0001383	53.03	gold quality
monocyte	CL:0000576	52.66	silver quality
prefrontal cortex	UBERON:0000451	51.07	gold quality
gastrocnemius	UBERON:0001388	50.98	gold quality
blood	UBERON:0000178	48.16	silver quality
placenta	UBERON:0001987	48.06	gold quality
adrenal gland	UBERON:0002369	46.48	gold quality
islet of Langerhans	UBERON:0000006	46.17	silver quality
adult mammalian kidney	UBERON:0000082	45.70	gold quality
subcutaneous adipose tissue	UBERON:0002190	45.56	gold quality
nucleus accumbens	UBERON:0001882	43.23	silver quality
superior frontal gyrus	UBERON:0002661	42.74	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	42.68	silver quality
body of pancreas	UBERON:0001150	42.64	silver quality
left adrenal gland cortex	UBERON:0035825	42.24	silver quality
putamen	UBERON:0001874	41.87	silver quality
body of stomach	UBERON:0001161	41.82	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.72	silver quality
right atrium auricular region	UBERON:0006631	41.41	silver quality
hypothalamus	UBERON:0001898	41.18	silver quality
esophagus	UBERON:0001043	41.11	gold quality
heart left ventricle	UBERON:0002084	41.05	silver quality
lower esophagus muscularis layer	UBERON:0035833	40.93	silver quality
right ovary	UBERON:0002118	40.79	silver quality
Ammon’s horn	UBERON:0001954	40.69	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	40.48	silver quality
left adrenal gland	UBERON:0001234	40.40	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.