LINC01605

Summary

LINC01605 (long intergenic non-protein coding RNA 1605, HGNC:51654) is a long non-coding RNA gene on chromosome 8p11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51654
Approved symbol	LINC01605
Name	long intergenic non-protein coding RNA 1605
Location	8p11.23
Locus type	RNA, long non-coding
Status	Approved
Aliases	ODIR1, lncGALM, LincDUSP, RP11-527N22.2, TCONS_00014973
Ensembl gene	ENSG00000253161
Ensembl biotype	lncRNA
Entrez	100507420
RNAcentral	URS0002123212 — lncRNA, 1436 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 176 — 176 lncRNA

ENST00000517363, ENST00000517714, ENST00000519691, ENST00000519738, ENST00000520422, ENST00000521989, ENST00000522471, ENST00000522718, ENST00000665151, ENST00000668286, ENST00000688477, ENST00000701647, ENST00000783999, ENST00000784000, ENST00000784001, ENST00000784002, ENST00000784003, ENST00000784004, ENST00000784005, ENST00000784006, ENST00000784007, ENST00000784008, ENST00000784009, ENST00000784010, ENST00000784011, ENST00000784012, ENST00000784013, ENST00000784014, ENST00000784015, ENST00000784016, ENST00000784017, ENST00000784018, ENST00000784019, ENST00000784020, ENST00000784021, ENST00000784022, ENST00000784023, ENST00000784024, ENST00000784025, ENST00000784026, ENST00000784027, ENST00000784028, ENST00000784029, ENST00000784030, ENST00000784031, ENST00000784032, ENST00000784033, ENST00000784034, ENST00000784035, ENST00000784036, ENST00000784037, ENST00000784038, ENST00000784039, ENST00000784040, ENST00000784041, ENST00000784042, ENST00000784043, ENST00000784044, ENST00000784045, ENST00000784046, ENST00000784047, ENST00000784048, ENST00000784049, ENST00000784050, ENST00000784051, ENST00000784052, ENST00000784053, ENST00000784054, ENST00000784055, ENST00000784056, ENST00000784057, ENST00000784058, ENST00000784059, ENST00000784060, ENST00000784061, ENST00000784062, ENST00000784063, ENST00000784064, ENST00000784065, ENST00000784066, ENST00000784067, ENST00000784068, ENST00000784069, ENST00000784070, ENST00000784071, ENST00000784072, ENST00000784073, ENST00000784074, ENST00000784075, ENST00000784076, ENST00000784077, ENST00000784078, ENST00000784079, ENST00000784080, ENST00000784081, ENST00000784082, ENST00000784083, ENST00000784084, ENST00000784085, ENST00000784086, ENST00000784087, ENST00000784088, ENST00000784089, ENST00000784090, ENST00000784091, ENST00000784092, ENST00000784093, ENST00000784094, ENST00000784095, ENST00000784096, ENST00000784097, ENST00000784098, ENST00000784099, ENST00000784100, ENST00000784101, ENST00000784102, ENST00000784103, ENST00000784104, ENST00000784105, ENST00000784106, ENST00000784107, ENST00000784108, ENST00000784109, ENST00000784110, ENST00000784111, ENST00000784112, ENST00000784113, ENST00000784114, ENST00000784115, ENST00000784116, ENST00000784117, ENST00000784118, ENST00000784119, ENST00000784120, ENST00000784121, ENST00000784122, ENST00000784123, ENST00000784124, ENST00000784125, ENST00000784126, ENST00000784127, ENST00000784128, ENST00000784129, ENST00000784130, ENST00000784131, ENST00000784132, ENST00000784133, ENST00000784134, ENST00000784135, ENST00000784136, ENST00000784137, ENST00000784138, ENST00000784139, ENST00000784140, ENST00000784141, ENST00000784536, ENST00000784537, ENST00000784538, ENST00000784539, ENST00000784540, ENST00000784541, ENST00000784542, ENST00000784543, ENST00000784544, ENST00000784545, ENST00000784546, ENST00000784547, ENST00000784548, ENST00000784549, ENST00000784550, ENST00000784551, ENST00000784552, ENST00000784553, ENST00000784554, ENST00000784985, ENST00000784986

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517363 — 8 exons

Exon	Start	End
ENSE00002108185	37475842	37476012
ENSE00002123020	37529097	37529190
ENSE00002126962	37473078	37473210
ENSE00002135527	37421341	37421569
ENSE00004158528	37406635	37407019
ENSE00004158568	37569726	37569993
ENSE00004158615	37554022	37554157
ENSE00004158620	37599061	37599094

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 81.96.

FANTOM5 (CAGE): breadth broad, TPM avg 2.5267 / max 199.4382, expressed in 601 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
92696	2.1947	559
92697	0.2122	123
92699	0.1030	42
92701	0.0106	3
92700	0.0062	3

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.96	silver quality
esophagus mucosa	UBERON:0002469	76.47	gold quality
stromal cell of endometrium	CL:0002255	75.96	gold quality
lower esophagus mucosa	UBERON:0035834	75.79	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	75.19	gold quality
tonsil	UBERON:0002372	66.12	gold quality
esophagus	UBERON:0001043	65.95	gold quality
vagina	UBERON:0000996	64.53	gold quality
prefrontal cortex	UBERON:0000451	64.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.34	gold quality
tibial artery	UBERON:0007610	63.57	gold quality
popliteal artery	UBERON:0002250	63.55	gold quality
cortical plate	UBERON:0005343	63.37	gold quality
endocervix	UBERON:0000458	63.16	gold quality
uterine cervix	UBERON:0000002	62.01	gold quality
right coronary artery	UBERON:0001625	61.89	gold quality
anterior cingulate cortex	UBERON:0009835	61.71	gold quality
right uterine tube	UBERON:0001302	61.63	gold quality
smooth muscle tissue	UBERON:0001135	61.20	gold quality
sural nerve	UBERON:0015488	61.17	silver quality
frontal cortex	UBERON:0001870	61.09	gold quality
superior frontal gyrus	UBERON:0002661	60.59	gold quality
rectum	UBERON:0001052	60.55	gold quality
skin of abdomen	UBERON:0001416	60.54	gold quality
vermiform appendix	UBERON:0001154	60.27	gold quality
ectocervix	UBERON:0012249	60.01	gold quality
endometrium	UBERON:0001295	59.52	gold quality
islet of Langerhans	UBERON:0000006	59.49	gold quality
placenta	UBERON:0001987	59.35	gold quality
monocyte	CL:0000576	59.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.04

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 6)

• key role of lincDUSP in the regulation of important pathways in colon cancer (PMID:29743621)
• LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p. (PMID:31841192)
• LINC01605 regulates proliferation, migration and invasion of colorectal cancer cells via targeting miR-3960/SOX11. (PMID:33629302)
• LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple-negative breast cancer. (PMID:35411612)
• LINC01605 Is a Novel Target of Mutant p53 in Breast and Ovarian Cancer Cell Lines. (PMID:37762037)
• LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis. (PMID:38734188)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.