LINC01606

Summary

LINC01606 (long intergenic non-protein coding RNA 1606, HGNC:51656) is a long non-coding RNA gene on chromosome 8q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51656
Approved symbol	LINC01606
Name	long intergenic non-protein coding RNA 1606
Location	8q12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_l2_00027778
Ensembl gene	ENSG00000253301
Ensembl biotype	lncRNA
Entrez	100507651
RNAcentral	URS000075EDE1 — lncRNA, 2813 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000517611, ENST00000518556, ENST00000519160, ENST00000519241, ENST00000519314, ENST00000520929, ENST00000521132, ENST00000521653, ENST00000523341, ENST00000654770, ENST00000655011, ENST00000655105, ENST00000657454, ENST00000659585, ENST00000661539, ENST00000661856, ENST00000667730, ENST00000668087, ENST00000669200, ENST00000764420, ENST00000764421, ENST00000764422, ENST00000764423, ENST00000764424, ENST00000764425, ENST00000764426, ENST00000764427, ENST00000764428, ENST00000764429, ENST00000764430, ENST00000764431, ENST00000764432, ENST00000764433, ENST00000764434, ENST00000764435, ENST00000764436, ENST00000764437, ENST00000764438, ENST00000764439, ENST00000764440, ENST00000764441, ENST00000764442

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517611 — 3 exons

Exon	Start	End
ENSE00002089873	57220111	57220295
ENSE00002128180	57219379	57219623
ENSE00002134350	57220589	57220738

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 98.79.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3030 / max 139.3853, expressed in 70 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
88953	0.1509	43
205191	0.0528	21
88949	0.0305	12
88951	0.0296	12
88948	0.0129	8
88952	0.0116	7
88954	0.0091	4
88950	0.0056	2

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	98.79	gold quality
right testis	UBERON:0004534	98.52	gold quality
testis	UBERON:0000473	97.55	gold quality
metanephros cortex	UBERON:0010533	88.81	gold quality
adult mammalian kidney	UBERON:0000082	87.45	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.68	gold quality
kidney	UBERON:0002113	86.26	gold quality
sural nerve	UBERON:0015488	82.01	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.10	gold quality
cortex of kidney	UBERON:0001225	78.10	gold quality
ganglionic eminence	UBERON:0004023	73.56	gold quality
ventricular zone	UBERON:0003053	73.29	gold quality
cortical plate	UBERON:0005343	69.55	gold quality
adenohypophysis	UBERON:0002196	67.08	gold quality
pituitary gland	UBERON:0000007	65.40	gold quality
right adrenal gland cortex	UBERON:0035827	63.84	gold quality
liver	UBERON:0002107	62.68	gold quality
monocyte	CL:0000576	60.61	gold quality
superior frontal gyrus	UBERON:0002661	58.11	gold quality
tonsil	UBERON:0002372	58.02	gold quality
prefrontal cortex	UBERON:0000451	56.73	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.46	gold quality
right lobe of liver	UBERON:0001114	55.90	gold quality
lymph node	UBERON:0000029	55.01	gold quality
mucosa of stomach	UBERON:0001199	55.01	gold quality
endocervix	UBERON:0000458	54.98	gold quality
right adrenal gland	UBERON:0001233	54.98	gold quality
frontal cortex	UBERON:0001870	54.73	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.68	gold quality
blood	UBERON:0000178	54.66	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	66.34
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01606 might be associated with miR-423-5p to regulate the level to which the Wnt/beta-catenin signaling pathway is activated. (PMID:30142387)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.